App
Customer Support
GBP
Find Bookings
Trip.com
>
Cheap Flights
>
Cuba
>
Santiago de Cuba
>
Santiago
>
Mexico City to Santiago flight
>
Mexico City International Airport to Santiago flight
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Cheap Flights from Mexico City International Airport to Santiago

Search for flights from Mexico City International Airport to Santiago and check out affordable one-way and round-trip options.

  • One way
  • Round-trip
      • MEX11:15
        26h 45m
        1 stop
        SCU16:00
        Mexico City - Santiago|Mon, Apr 28|Aeromexico
        £332£732
        55% OFF
        55% OFF
        £732£332

        Choose Aeromexico flights from Mexico City to Santiago. The one-way connecting flight with Aeromexico departs from Mexico City International Airport on Mon, Apr 28, arriving at Antonio Maceo International Airport. One-way Prices start from £332 including taxes and charges.

      • MEX11:15
        11h 5m
        1 stop
        SCU00:20
        Mexico City - Santiago|Tue, Apr 22|Aeromexico
        £349£732
        52% OFF
        52% OFF
        £732£349

        Choose Aeromexico flights from Mexico City to Santiago. The one-way connecting flight with Aeromexico departs from Mexico City International Airport on Tue, Apr 22, arriving at Antonio Maceo International Airport. One-way Prices start from £349 including taxes and charges.

      • MEX11:10
        10h 25m
        1 stop
        SCU23:35
        Mexico City - Santiago|Thu, May 22|Aeromexico
        £433£732
        41% OFF
        41% OFF
        £732£433

        Choose Aeromexico flights from Mexico City to Santiago. The one-way connecting flight with Aeromexico departs from Mexico City International Airport on Thu, May 22, arriving at Antonio Maceo International Airport. One-way Prices start from £433 including taxes and charges.

      • MEX11:10
        9h 25m
        1 stop
        SCU22:35
        Mexico City - Santiago|Thu, May 15|Aeromexico
        £454
        £454

        Choose Aeromexico flights from Mexico City to Santiago. The one-way connecting flight with Aeromexico departs from Mexico City International Airport on Thu, May 15, arriving at Antonio Maceo International Airport. One-way Prices start from £454 including taxes and charges.

      • MEX11:15
        9h 20m
        1 stop
        SCU22:35
        Mexico City - Santiago|Thu, Apr 17|Aeromexico
        £651
        £651

        Choose Aeromexico flights from Mexico City to Santiago. The one-way connecting flight with Aeromexico departs from Mexico City International Airport on Thu, Apr 17, arriving at Antonio Maceo International Airport. One-way Prices start from £651 including taxes and charges.

      • MEX1:00 PM
        3h 5m
        Nonstop
        SCU2:00 PM
        Mexico City - Santiago|Thu, Apr 10|Aeromexico
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Airports in Santiago

Learn about different airports in Santiago, find the best flight and transfer options, and plan your journey.

  • 0 km from central Santiago
    Antonio Maceo International Airport
    Tickets From
    £328

Flight Schedule from Mexico City International Airport to Santiago

Check the schedule for flights from Mexico City International Airport to Santiago and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. CM149

    Copa Airlines

    01:40

    MEX

    3.6h

    06:18

    PTY

    SMTWTFS
    Search

  2. CM345

    Copa Airlines

    09:32

    PTY

    2.8h

    13:17

    HAV

    SMTW-FS

  3. CU470

    Cubana Airlines

    22:50

    HAV

    1.5h

    00:20

    SCU

    -M-W---

  4. CM137

    Copa Airlines

    09:50

    MEX

    3.7h

    14:33

    PTY

    SMTWTFS
    Search

  5. CM387

    Copa Airlines

    18:40

    PTY

    2.8h

    22:25

    HAV

    S-T--F-

  6. CU7980

    Cubana Airlines

    14:30

    HAV

    1.5h

    16:00

    SCU

    -M-----

  7. AM451

    Aeromexico

    10:55

    MEX

    3.1h

    16:00

    HAV

    SMTWTFS
    Search

  8. CU7980

    Cubana Airlines

    14:30

    HAV

    1.5h

    16:00

    SCU

    -M-----

  9. AM451

    Aeromexico

    10:55

    MEX

    3.1h

    16:00

    HAV

    SMTWTFS
    Search

  10. CU470

    Cubana Airlines

    22:50

    HAV

    1.5h

    00:20

    SCU

    -M-W---

  11. AM451

    Aeromexico

    10:55

    MEX

    3.1h

    16:00

    HAV

    SMTWTFS
    Search

  12. CU7986

    Cubana Airlines

    22:20

    HAV

    1.3h

    23:35

    SCU

    ---W---

  13. VB1374

    Viva

    23:05

    MEX

    2.2h

    02:15

    CUN

    SMTWTFS
    Search

  14. VB312

    Viva

    07:05

    CUN

    1.1h

    09:10

    HAV

    SM-WTFS

  15. CU7986

    Cubana Airlines

    22:20

    HAV

    1.3h

    23:35

    SCU

    ---W---

  16. VB1374

    Viva

    23:05

    MEX

    2.2h

    02:15

    CUN

    SMTWTFS
    Search

  17. VB312

    Viva

    07:05

    CUN

    1.1h

    09:10

    HAV

    SM-WTFS

  18. CU470

    Cubana Airlines

    22:50

    HAV

    1.5h

    00:20

    SCU

    -M-W---

  19. VB1374

    Viva

    23:05

    MEX

    2.2h

    02:15

    CUN

    SMTWTFS
    Search

  20. VB312

    Viva

    07:05

    CUN

    1.1h

    09:10

    HAV

    SM-WTFS

  21. CU7980

    Cubana Airlines

    14:30

    HAV

    1.5h

    16:00

    SCU

    -M-----
Find more flights and airlines

Flight Info of Flights from Mexico City International Airport to Santiago

Cheapest one-way flight price£328
Off-season travel monthMarch
Peak season for travelJanuary

FAQs for Mexico City International Airport to Santiago Flights

  • How many airports in Santiago (SCU)?

    There are 1 airport(s) in Santiago (SCU): Antonio Maceo International Airport.

  • What is the transportation method from the main airport to downtown in Santiago?

    • The distance from Antonio Maceo International Airport to downtown is about 27km, by taxi about 40 minutes.

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.