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O'Hare International Airport to Des Moines International Airport flight
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O'Hare International Airport to Des Moines International Airport Flights Info

Cheapest one-way
€108
American Airlines American Airlines 1h 43m · Direct Wed, Dec 30
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Cheapest return
€216
American Airlines American Airlines 1h 33m · Direct Tue, Nov 17 - Thu, Nov 19
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Recommended airlines
American Airlines American AirlinesCheapest· From €108 American Airlines American AirlinesMost booked

Explore the cheapest one-way and round-trip flights from O'Hare International Airport to Des Moines International Airport over the next 90 days, with one-way fares from €108 and round-trip from €216. Based on Trip.com's latest 7-day flight data.

    • Cheapest nonstop
      ORD 22:53
      1h 33m
      Direct
      DSM 00:26
      Chicago - Des Moines | Tue, Nov 17 | American Airlines
      DSM 13:58
      1h 46m
      Direct
      ORD 15:44
      Des Moines - Chicago | Thu, Nov 19 | American Airlines
      €216 €661
      67% off
      67% off
      €661 €216
    • ORD 07:35
      1h 37m
      Direct
      DSM 09:12
      Chicago - Des Moines | Wed, Dec 30 | American Airlines
      DSM 05:30
      1h 50m
      Direct
      ORD 07:20
      Des Moines - Chicago | Fri, Jan 1 | American Airlines
      €310 €661
      53% off
      53% off
      €661 €310
    • ORD 11:51
      1h 36m
      Direct
      DSM 13:27
      Chicago - Des Moines | Tue, Dec 8 | American Airlines
      DSM 19:24
      1h 50m
      Direct
      ORD 21:14
      Des Moines - Chicago | Fri, Dec 11 | American Airlines
      €318 €661
      52% off
      52% off
      €661 €318
    • ORD 08:50
      1h 42m
      Direct
      DSM 10:32
      Chicago - Des Moines | Tue, Dec 8 | United Airlines
      DSM 09:25
      1h 49m
      Direct
      ORD 11:14
      Des Moines - Chicago | Fri, Dec 11 | American Airlines
      €365
      45% off
      €661 €365
    • ORD 07:35
      1h 37m
      Direct
      DSM 09:12
      Chicago - Des Moines | Mon, Jan 11 | American Airlines
      DSM 09:40
      1h 53m
      Direct
      ORD 11:33
      Des Moines - Chicago | Thu, Jan 14 | American Airlines
      €399
      40% off
      €661 €399
    • ORD 21:31
      1h 46m
      Direct
      DSM 23:17
      Chicago - Des Moines | Mon, Jan 11 | United Airlines
      DSM 08:00
      1h 44m
      Direct
      ORD 09:44
      Des Moines - Chicago | Thu, Jan 14 | United Airlines
      €444
      33% off
      €661 €444
    • ORD 06:20
      3h 51m
      1 stop
      DSM 10:11
      Chicago - Des Moines | Tue, Nov 17 | Delta Air Lines
      DSM 10:57
      5h 50m
      1 stop
      MDW 16:47
      Des Moines - Chicago | Thu, Nov 19 | Delta Air Lines
      €227
      66% off
      €661 €227
    • ORD 20:25
      1h 30m
      Direct
      DSM 21:55
      Chicago - Des Moines | Tue, Nov 17 | United Airlines
      DSM 10:57
      3h 39m
      1 stop
      ORD 14:36
      Des Moines - Chicago | Thu, Nov 19 | Delta Air Lines
      €262
      60% off
      €661 €262
    • ORD 09:59
      6h 12m
      1 stop
      DSM 16:11
      Chicago - Des Moines | Wed, Dec 30 | Delta Air Lines
      DSM 20:26
      28h
      1 stop
      ORD 00:26
      Des Moines - Chicago | Fri, Jan 1 | Frontier Airlines
      €298
      55% off
      €661 €298
    • CHI 13:00
      17h 25m
      1 stop
      DSM 14:00
      Chicago - Des Moines | Tue, Nov 17 | Normal Airline
      DSM 15:00
      6h
      Direct
      CHI 16:00
      Des Moines - Chicago | Thu, Nov 19 | Normal Airline
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    • Cheapest
      ORD 21:00
      1h 43m
      Direct
      DSM 22:43
      Chicago - Des Moines | Wed, Dec 30 | American Airlines
      €108 €240
      55% off
      55% off
      €240 €108
    • ORD 11:50
      1h 45m
      Direct
      DSM 13:35
      Chicago - Des Moines | Mon, Dec 21 | American Airlines
      €109 €180
      39% off
      39% off
      €180 €109
    • ORD 22:53
      1h 33m
      Direct
      DSM 00:26
      Chicago - Des Moines | Tue, Nov 24 | American Airlines
      €109 €180
      39% off
      39% off
      €180 €109
    • ORD 22:45
      1h 34m
      Direct
      DSM 00:19
      Chicago - Des Moines | Sun, Dec 13 | American Airlines
      €112
      38% off
      €180 €112
    • ORD 06:20
      4h 1m
      1 stop
      DSM 10:21
      Chicago - Des Moines | Sun, Dec 13 | Delta Air Lines
      €112
      38% off
      €180 €112
    • ORD 06:20
      4h 1m
      1 stop
      DSM 10:21
      Chicago - Des Moines | Mon, Dec 21 | Delta Air Lines
      €114
      37% off
      €180 €114
    • ORD 06:23
      3h 56m
      1 stop
      DSM 10:19
      Chicago - Des Moines | Tue, Nov 24 | Delta Air Lines
      €115
      36% off
      €180 €115
    • ORD 20:45
      1h 44m
      Direct
      DSM 22:29
      Chicago - Des Moines | Sat, Jan 16 | American Airlines
      €119
      50% off
      €240 €119
    • ORD 17:29
      1h 40m
      Direct
      DSM 19:09
      Chicago - Des Moines | Sat, Dec 19 | American Airlines
      €119
      50% off
      €240 €119
    • CHI 13:00
      17h 25m
      1 stop
      DSM 14:00
      Chicago - Des Moines | Tue, Nov 17 | Normal Airline
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    • Cheapest nonstop
      ORD 21:00
      1h 43m
      Direct
      DSM 22:43
      Chicago - Des Moines | Wed, Dec 30 | American Airlines
      €108 €240
      55% off
      55% off
      €240 €108
    • ORD 11:50
      1h 45m
      Direct
      DSM 13:35
      Chicago - Des Moines | Mon, Dec 21 | American Airlines
      €109 €180
      39% off
      39% off
      €180 €109
    • ORD 22:53
      1h 33m
      Direct
      DSM 00:26
      Chicago - Des Moines | Tue, Nov 24 | American Airlines
      €109 €180
      39% off
      39% off
      €180 €109
    • ORD 22:45
      1h 34m
      Direct
      DSM 00:19
      Chicago - Des Moines | Sun, Dec 13 | American Airlines
      €112
      38% off
      €180 €112
    • ORD 20:45
      1h 44m
      Direct
      DSM 22:29
      Chicago - Des Moines | Sat, Jan 16 | American Airlines
      €119
      50% off
      €240 €119
    • ORD 17:29
      1h 40m
      Direct
      DSM 19:09
      Chicago - Des Moines | Sat, Dec 19 | American Airlines
      €119
      50% off
      €240 €119
    • ORD 17:19
      1h 36m
      Direct
      DSM 18:55
      Chicago - Des Moines | Thu, Dec 3 | American Airlines
      €131
      27% off
      €180 €131
    • ORD 17:21
      1h 40m
      Direct
      DSM 19:01
      Chicago - Des Moines | Sat, Dec 5 | American Airlines
      €135
      44% off
      €240 €135
    • ORD 23:00
      1h 40m
      Direct
      DSM 00:40
      Chicago - Des Moines | Thu, Dec 17 | American Airlines
      €136
      24% off
      €180 €136
    • CHI 13:00
      17h 25m
      1 stop
      DSM 14:00
      Chicago - Des Moines | Tue, Nov 17 | Normal Airline
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    • Cheapest nonstop
      ORD 21:00
      1h 43m
      Direct
      DSM 22:43
      Chicago - Des Moines | Wed, Dec 30 | American Airlines
      €108 €274
      61% off
      61% off
      €274 €108
    • ORD 20:45
      1h 44m
      Direct
      DSM 22:29
      Chicago - Des Moines | Sat, Jan 16 | American Airlines
      €119 €274
      56% off
      56% off
      €274 €119
    • ORD 17:29
      1h 40m
      Direct
      DSM 19:09
      Chicago - Des Moines | Sat, Dec 19 | American Airlines
      €119 €274
      56% off
      56% off
      €274 €119
    • ORD 17:21
      1h 40m
      Direct
      DSM 19:01
      Chicago - Des Moines | Sat, Dec 5 | American Airlines
      €135
      51% off
      €274 €135
    • ORD 17:18
      1h 36m
      Direct
      DSM 18:54
      Chicago - Des Moines | Fri, Nov 27 | American Airlines
      €139
      49% off
      €274 €139
    • ORD 17:21
      1h 35m
      Direct
      DSM 18:56
      Chicago - Des Moines | Tue, Dec 8 | American Airlines
      €143
      48% off
      €274 €143
    • ORD 17:21
      1h 40m
      Direct
      DSM 19:01
      Chicago - Des Moines | Sun, Dec 6 | American Airlines
      €159
      42% off
      €274 €159
    • ORD 17:29
      1h 44m
      Direct
      DSM 19:13
      Chicago - Des Moines | Fri, Jan 15 | American Airlines
      €174
      36% off
      €274 €174
    • ORD 21:00
      1h 43m
      Direct
      DSM 22:43
      Chicago - Des Moines | Mon, Jan 4 | American Airlines
      €182
      34% off
      €274 €182
    • CHI 13:00
      17h 25m
      1 stop
      DSM 14:00
      Chicago - Des Moines | Tue, Nov 17 | Normal Airline
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    • Cheapest nonstop
      ORD 22:53
      1h 33m
      Direct
      DSM 00:26
      Chicago - Des Moines | Mon, Nov 16 | American Airlines
      €218 €266
      18% off
      18% off
      €266 €218
    • ORD 09:59
      4h 9m
      1 stop
      DSM 14:08
      Chicago - Des Moines | Sat, Nov 21 | Delta Air Lines
      €135 €266
      49% off
      49% off
      €266 €135
    • CHI 13:00
      17h 25m
      1 stop
      DSM 14:00
      Chicago - Des Moines | Tue, Nov 17 | Normal Airline
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      Find more flights
    • ORD 12:50
      1h 24m
      Direct
      DSM 14:14
      Chicago - Des Moines | Sun, Dec 6 | United Airlines
      €199 €366
      46% off
      46% off
      €366 €199
    • ORD 16:00
      1h 28m
      Direct
      DSM 17:28
      Chicago - Des Moines | Mon, Nov 16 | United Airlines
      €248 €366
      32% off
      32% off
      €366 €248
    • ORD 16:00
      1h 28m
      Direct
      DSM 17:28
      Chicago - Des Moines | Fri, Nov 27 | United Airlines
      €252 €366
      31% off
      31% off
      €366 €252
    • ORD 11:10
      1h 29m
      Direct
      DSM 12:39
      Chicago - Des Moines | Sat, Dec 5 | United Airlines
      €175
      52% off
      €366 €175
    • ORD 22:53
      1h 33m
      Direct
      DSM 00:26
      Chicago - Des Moines | Tue, Nov 24 | American Airlines
      €109
      39% off
      €180 €109
    • ORD 22:45
      1h 34m
      Direct
      DSM 00:19
      Chicago - Des Moines | Sun, Dec 13 | American Airlines
      €112
      38% off
      €180 €112
    • ORD 21:25
      1h 34m
      Direct
      DSM 22:59
      Chicago - Des Moines | Fri, Nov 27 | United Airlines
      €187
      22% off
      €240 €187
    • ORD 17:21
      1h 35m
      Direct
      DSM 18:56
      Chicago - Des Moines | Tue, Dec 8 | American Airlines
      €143
      40% off
      €240 €143
    • ORD 13:00
      1h 35m
      Direct
      DSM 14:35
      Chicago - Des Moines | Wed, Dec 30 | United Airlines
      €202
      45% off
      €366 €202
    • CHI 13:00
      17h 25m
      1 stop
      DSM 14:00
      Chicago - Des Moines | Tue, Nov 17 | Normal Airline
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Displayed flight fares from Chicago to Des Moines are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Which airline offers the cheapest flights from O'Hare International Airport to Des Moines International Airport?

The cheapest airline flying from O'Hare International Airport to Des Moines International Airport is American Airlines (from €108) among 1 carriers operating this route. Based on Trip.com's latest 7-day flight data.
easyJet logo easyJet Wizz Air UK logo Wizz Air UK British Airways logo British Airways Jet2.com logo Jet2.com Virgin Atlantic logo Virgin Atlantic
American Airlines logo American Airlines

What is the flight schedule from O'Hare International Airport to Des Moines International Airport?

Check the schedule for flights from Chicago to Des Moines and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. UA1839

    O'Hare International Airport

    19:45

    ORD

    1h 32m

    21:17

    DSM

    S M T W T F S
    Search

  2. AA6229

    O'Hare International Airport

    11:51

    ORD

    1h 37m

    13:28

    DSM

    - - - W T F S
    Search

  3. AA4711

    O'Hare International Airport

    17:21

    ORD

    1h 35m

    18:56

    DSM

    S M T W T F S
    Search

  4. AA4548

    O'Hare International Airport

    20:45

    ORD

    1h 43m

    22:28

    DSM

    S M T W T F S
    Search

  5. DL1306

    O'Hare International Airport

    17:20

    ORD

    1h 35m

    Direct

    18:55

    MSP

    S M T W T F S
    Search

  6. DL5253

    Minneapolis-Saint Paul International Airport

    20:05

    MSP

    1h 19m

    Direct

    21:24

    DSM

    S M T W T F S

  7. DL1717

    O'Hare International Airport

    06:00

    ORD

    1h 36m

    Direct

    07:36

    MSP

    S M T W T F S
    Search

  8. DL4998

    Minneapolis-Saint Paul International Airport

    09:00

    MSP

    1h 20m

    Direct

    10:20

    DSM

    S M T W T F S

  9. DL1533

    O'Hare International Airport

    15:47

    ORD

    1h 33m

    Direct

    17:20

    MSP

    S M T W T F S
    Search

  10. DL5253

    Minneapolis-Saint Paul International Airport

    20:05

    MSP

    1h 19m

    Direct

    21:24

    DSM

    S M T W T F S

  11. F91483

    O'Hare International Airport

    11:47

    ORD

    2h 59m

    Direct

    13:46

    DEN

    S M T W T F S
    Search

  12. F91678

    Denver International Airport

    16:59

    DEN

    1h 46m

    Direct

    19:45

    DSM

    S - - - - - S
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FAQs for O'Hare International Airport to Des Moines International Airport Flights

  • How long is the flight from O'Hare International Airport to Des Moines International Airport?

    O'Hare International Airport to Des Moines International Airport takes about 56 minutes on average. Actual flight time may vary depending on route, weather and air traffic.
  • There are around 9 daily flights from O'Hare International Airport (ORD) to Des Moines International Airport (DSM).
  • The earliest flight from O'Hare International Airport to Des Moines International Airport departs at 07:14, and the last departs at 22:53, with about 11 flights per day. Flight times may change, so please check the latest departure and arrival times before you travel.
  • The route from O'Hare International Airport (ORD) to Des Moines International Airport (DSM) is quite popular. Without considering departure times or holidays, tickets cost around €275 in November, the most expensive month to book this route.
  • American Airlines is a very popular airline operating an average of 543 flights per month.
  • One-way flights from O'Hare International Airport to Des Moines International Airport currently start from €109, and round-trip fares start from €216. The current lowest fare is a American Airlines flight departing on Mon, Dec 21; prices may vary depending on availability.
  • Yes. United Airlines and American Airlines operate direct flights from O'Hare International Airport to Des Moines International Airport, with an average flight time of 51 minutes, and around 70 weekly flights. Actual flight frequency may vary by season.
  • Based on Trip.com flight data for departures within the next 30 days with at most one stop, the average one-way price from O'Hare International Airport to Des Moines International Airport is €211. Prices may vary depending on the departure date, airline, and availability.
  • O'Hare International Airport to Des Moines International Airport operates around 71 weekly flights, mainly by United Airlines and American Airlines. Actual frequency may vary during holidays and seasonal schedule adjustments.
  • Enter O'Hare International Airport and Des Moines International Airport, select your departure date and number of passengers, then compare flights by price, flight duration, and baggage allowance. Once you've chosen a fare, review the change and refund rules, fill in passenger details, and pay to receive your booking confirmation.

Find Cheap Flights with Trip.com

Note: Prices shown on this page are the estimated lowest prices and include all taxes and fees found in the last 24 hours.

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Prices displayed on this page are all-inclusive (including taxes, fuel surcharges, civil aviation development fund, etc.), with all fees confirmed before payment. Fees for luggage, meals, Wi-Fi, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page have been updated within the last 24 hours—sometimes even in real time. The more popular the route, the more accurate the data.

Change & Cancellation Policy

Trip.com shows the cancellation and change policies for each flight ticket during the booking process, including any fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply according to the airline's ticket policy.
Cancellation/change due to a flight schedule change:
If the flight schedule has changed and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please visit the customer support pages.