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Flights from Charleston to Santo Domingo
Flight deals from Charleston to Santo Domingo
We've found these cheap flights for you. You can book one-way or return flight tickets.
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Round-trip
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One way
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CHS 05:357h 43m1 stopsSDQ 13:18Charleston - Santo Domingo | Thu, Apr 24 | Delta Air LinesSDQ 14:439h 15m1 stopsCHS 23:58Santo Domingo - Charleston | Sun, Apr 27 | Delta Air Lines£339 £59543% OFF43% OFF£595 £339
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CHS 12:3010h 26m1 stopsSDQ 22:56Charleston - Santo Domingo | Sat, Apr 26 | Jetblue AirwaysSDQ 17:5715h 39m1 stopsCHS 09:36Santo Domingo - Charleston | Sat, May 3 | Jetblue Airways£362 £59539% OFF39% OFF£595 £362
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CHS 10:3212h 8m1 stopsSDQ 22:40Charleston - Santo Domingo | Thu, Apr 10 | American AirlinesSDQ 05:0018h 41m1 stopsCHS 23:41Santo Domingo - Charleston | Mon, Apr 14 | American Airlines£369 £59538% OFF38% OFF£595 £369
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CHS 19:1819h 54m1 stopsSDQ 15:12Charleston - Santo Domingo | Sat, Apr 12 | American AirlinesSDQ 06:5027h 1m1 stopsCHS 09:51Santo Domingo - Charleston | Wed, Apr 16 | American Airlines£36938% OFF£595 £369
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CHS 06:0019h 50m1 stopsSDQ 01:50Charleston - Santo Domingo | Sat, May 3 | United AirlinesSDQ 03:1512h 35m1 stopsCHS 15:50Santo Domingo - Charleston | Tue, May 6 | Jetblue Airways£37537% OFF£595 £375
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CHS 14:269h 53m1 stopsSDQ 00:19Charleston - Santo Domingo | Tue, May 20 | Delta Air LinesSDQ 14:416h 23m1 stopsCHS 21:04Santo Domingo - Charleston | Tue, May 27 | Delta Air Lines£43427% OFF£595 £434
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CHS 14:2610h 8m1 stopsSDQ 00:34Charleston - Santo Domingo | Thu, May 29 | Delta Air LinesSDQ 07:009h 35m1 stopsCHS 16:35Santo Domingo - Charleston | Sun, Jun 1 | Delta Air Lines£43427% OFF£595 £434
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CHS 18:2917h 26m1 stopsSDQ 11:55Charleston - Santo Domingo | Wed, May 28 | United AirlinesSDQ 06:0017h 59m1 stopsCHS 23:59Santo Domingo - Charleston | Sun, Jun 1 | United Airlines£43826% OFF£595 £438
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CHS 06:0019h 50m1 stopsSDQ 01:50Charleston - Santo Domingo | Sun, Apr 6 | United AirlinesSDQ 06:0012h 37m1 stopsCHS 18:37Santo Domingo - Charleston | Tue, Apr 8 | United Airlines£45124% OFF£595 £451
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CHS 06:0015h 27m1 stopsSDQ 21:27Charleston - Santo Domingo | Sat, Apr 26 | United AirlinesSDQ 17:5724h 50m1 stopsCHS 18:47Santo Domingo - Charleston | Sat, May 3 | Jetblue Airways£45224% OFF£595 £452
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CHS 13:0017h 25m1 stopsSDQ Invalid DateCharleston - Santo Domingo | Tue, Apr 8 | Normal AirlineSDQ 15:006hNonstopCHS 16:00Santo Domingo - Charleston | Thu, Apr 10 | Normal AirlineFind More FlightsFind More Flights
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CHS 07:0011h 28m1 stopsSDQ 18:28Charleston - Santo Domingo | Mon, May 12 | Delta Air Lines£179 £46962% OFF62% OFF£469 £179
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CHS 06:008h 10m1 stopsSDQ 14:10Charleston - Santo Domingo | Fri, May 2 | United Airlines£189 £46960% OFF60% OFF£469 £189
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CHS 06:008h 10m1 stopsSDQ 14:10Charleston - Santo Domingo | Fri, May 30 | United Airlines£189 £46960% OFF60% OFF£469 £189
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CHS 06:008h 10m1 stopsSDQ 14:10Charleston - Santo Domingo | Wed, Apr 9 | United Airlines£22652% OFF£469 £226
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CHS 06:008h 10m1 stopsSDQ 14:10Charleston - Santo Domingo | Mon, May 12 | United Airlines£23550% OFF£469 £235
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CHS 07:0018h 50m1 stopsSDQ 01:50Charleston - Santo Domingo | Fri, May 2 | Delta Air Lines£23949% OFF£469 £239
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CHS 06:0010h 49m1 stopsSDQ 16:49Charleston - Santo Domingo | Wed, Apr 16 | Jetblue Airways£30635% OFF£469 £306
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CHS 06:008h 10m1 stopsSDQ 14:10Charleston - Santo Domingo | Wed, Apr 16 | United Airlines£31433% OFF£469 £314
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CHS 10:2126h 8m1 stopsSDQ 12:29Charleston - Santo Domingo | Fri, Apr 11 | Jetblue Airways£32132% OFF£469 £321
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CHS 06:0019h 50m1 stopsSDQ 01:50Charleston - Santo Domingo | Sat, Apr 12 | United Airlines£35724% OFF£469 £357
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CHS 13:0017h 25m1 stopsSDQ Invalid DateCharleston - Santo Domingo | Tue, Apr 8 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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FAQ
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When are flight tickets from Charleston (CHS) to Santo Domingo (SDQ) the cheapest?
Airlines adjust prices for flights from Charleston to Santo Domingo based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much are flights from Charleston (CHS) to Santo Domingo (SDQ) cost?
According to Trip.com's data, the lowest price is around £442. -
What is the transportation method from the main airport to downtown in Santo Domingo?
- The distance from Las Américas International Airport to downtown is about 33km, by taxi about 50 minutes.
- The distance from La Isabela International Airport to downtown is about 8km, by taxi about 20 minutes.
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How many airports in Santo Domingo (SDQ)?
There are 2 airport(s) in Santo Domingo (SDQ): La Isabela International Airport and Las Américas International Airport.
How to find a cheap flight from Charleston to Santo Domingo
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Charleston to Santo Domingo. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest flight from Charleston to Santo Domingo.
Simply tap "Date" on the flight search bar to browse through the calendar and check out airfare from Charleston to Santo Domingo over the next 6 months in 2025. If you're planning to fly within the next three months, it looks like the most affordable option is on Mon, May 12, with one-way flights priced at just £179.
Compare cheap flight deals from Charleston to Santo Domingo across hundreds of airlines.
With our extensive search, you can compare prices from over 500 airlines to find the cheapest flight tickets from Charleston to Santo Domingo. The cheapest airline for this route is Delta Air Lines.
Set up a Price Alert
By setting up a Price Alert for your journey from Charleston to Santo Domingo, you can easily keep an eye on ticket prices without having to check every day.
Don't miss out on cheap flight deals and promo codes from Charleston to Santo Domingo.
You can always find the latest offers through Trip.com Deals and Promo Codes for cheap flights. By signing up for a free membership, you'll get access to even more deals for your flights.
Book early or wait until the last minute.
It's usually best to book early. Flight tickets are often cheapest when they're first released, typically about a year before the departure date. So, have a look online as soon as the flights you're interested in become available. If you miss the cheapest time, you might still find some good deals as the departure date gets closer.
Search for flights on the go.
For the best travel flight booking experience, download the Trip.com app. You can search for cheap flights from Charleston to Santo Domingo and snag some exclusive deals just for you.
Flight Information from Charleston to Santo Domingo
Cheapest one-way flight price | £178 |
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Off-season travel month | March |
Peak season for travel | May |
Flight distance | 1,896.86km |
Popular airline | Jetblue Airways |
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