£246 Cheap Flights from Spain to Panama
Easily compare flights from Spain to Panama and find the cheapest tickets available!
Madrid
Panama City
From £698
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Flying From Spain to Panama: What You Need to Know
| Cheapest one-way flight price | £246 |
|---|---|
| Cheapest return ticket price | £481 |
| Off-season travel month | September |
| Peak season for travel | July |
| Popular airline | Air Europa |
| Cheapest month | March |
Compare multiple airlines at once to find the best flight deals from Spain to Panama.
Airlines Flying From Spain to Panama
Air Europa 
avianca Search Flights From Spain to Panama
Easily compare flights from Spain to Panama and find the cheapest tickets available!
Find the Cheapest Flights to Panama From Spain
Looking for affordable flights from Spain to Panama? Check out these great prices for the next 90 days, starting at just £246 for a one-way ticket and £481 for a round-trip.
- Return
- One way
-
- Cheapest nonstop
Tue, May 19MAD|PTYMadridPanama CityDirect | Air EuropaWed, May 20PTY|MADPanama CityMadridDirect | Air Europa£472 £91949% off49% off£919 £472 -
Tue, May 19ALC|PTYAlicantePanama City1 stop | Air Europa
Mon, May 25PTY|ALCPanama CityAlicante1 stop | Air Europa£481 £91948% off48% off£919 £481
-
Tue, May 26BIO|PTYBilbaoPanama City1 stop | Air Europa
Thu, May 28PTY|BIOPanama CityBilbao1 stop | Air Europa£482 £91948% off48% off£919 £482
-
Tue, May 26BCN|PTYBarcelonaPanama City1 stop | Air Europa
Thu, May 28PTY|BCNPanama CityBarcelona1 stop | Air Europa£49047% off£919 £490
-
Wed, May 20VLC|PTYValenciaPanama City1 stop | Air Europa
Tue, May 26PTY|VLCPanama CityValencia1 stop | Air Europa£49346% off£919 £493
-
Fri, May 29AGP|PTYMalagaPanama City1 stop | Air Europa
Mon, Jun 1PTY|AGPPanama CityMalaga1 stop | Air Europa£49346% off£919 £493
-
Fri, May 22PMI|PTYPalma de MallorcaPanama City1 stop | Air Europa
Wed, May 27PTY|PMIPanama CityPalma de Mallorca1 stop | Air Europa£50945% off£919 £509
-
Mon, May 25LCG|PTYLa CorunaPanama City1 stop | Air Europa
Fri, May 29PTY|LCGPanama CityLa Coruna1 stop | Air Europa£51045% off£919 £510
-
Mon, May 18VGO|PTYVigoPanama City1 stop | Air Europa
Sun, May 24PTY|VGOPanama CityVigo1 stop | Air Europa£51644% off£919 £516
-
Wed, May 20TFN|PTYTenerifePanama City1 stop | Air Europa
Wed, May 27PTY|TFNPanama CityTenerife1 stop | Air Europa£55040% off£919 £550
-
Mon, Jun 15MAD|PTYMadridPanama City1 stop | avianca
Mon, Jun 22PTY|MADPanama CityMadrid1 stop | avianca£75318% off£919 £753 -
Sun, May 17BCN|PTYBarcelonaPanama City1 stop | Normal Airline
Tue, May 19PTY|BCNPanama CityBarcelonaDirect | Normal AirlineFind more flightsFind more flights
-
Cheapest nonstopThu, May 21MAD|PTYMadridPanama CityDirect | Air Europa£270 £41335% off35% off£413 £270
-
Thu, Jun 11BCN|PTYBarcelonaPanama City1 stop | avianca£246 £41340% off40% off£413 £246
-
Mon, May 18VLC|PTYValenciaPanama City1 stop | Air Europa£254 £41338% off38% off£413 £254
-
Tue, May 19BIO|PTYBilbaoPanama City1 stop | Air Europa£25638% off£413 £256
-
Mon, May 18LCG|PTYLa CorunaPanama City1 stop | Iberia£26735% off£413 £267 -
Fri, May 22AGP|PTYMalagaPanama City1 stop | Air Europa£26935% off£413 £269
-
Mon, May 18VGO|PTYVigoPanama City1 stop | Air Europa£27134% off£413 £271
-
Thu, May 28ALC|PTYAlicantePanama City1 stop | Air Europa£27334% off£413 £273
-
Mon, Jun 15MAD|PTYMadridPanama City1 stop | avianca£30825% off£413 £308
-
Sun, May 24PMI|PTYPalma de MallorcaPanama City1 stop | Air Europa£31524% off£413 £315
-
Wed, May 20TFN|PTYTenerifePanama City1 stop | Air Europa£33818% off£413 £338
-
Sun, May 17BCN|PTYBarcelonaPanama City1 stop | Normal AirlineFind more flightsFind more flights
Displayed flight fares from Spain to Panama are based on average prices across airlines over the next 3 months, according to the latest Trip.com data.
FAQs: Flights From Spain to Panama
When is it the cheapest time to fly from Spain to Panama?
According to our flights calendar over the next 90 days, it seems the cheapest date is on 2026-06-14 for one-way flights.How much is the cheapest flight ticket to Panama from Spain?
The cheapest return flight from Spain to Panama is on the route from Barcelona to Panama City, with prices starting at £454 for a return trip between 2026-06-14 and 2026-06-21.What is the cheapest airline that flies to Panama from Spain?
The cheapest airline flying to Panama from Spain is avianca serving the route from Barcelona to Panama City.What airlines fly from Spain to Panama?
Air Europa are airlines that fly frequently from Spain to Panama. The overall price will vary depending on your destination and travel dates. Budget airlines generally offer lower prices to Australia, but they may have limited baggage allowance, reduced onboard services, and longer commuting times to secondary airports.
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