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Flights from Grand Cayman to Panama City

Airlines operating flights from Grand Cayman to Panama City

Choose from 1 airlines flying from Grand Cayman to Panama City, including Cayman Airways, and . Cayman Airways currently offers the cheapest ticket on this route.
Cayman Airways logo Cayman Airways
Airlines are determined based on actual purchased flight tickets from Grand Cayman to Panama City according to previous 12 months data from Trip.com.

Find the cheapest direct flight options from Grand Cayman to Panama City over the next three months. Book one-way tickets from £292 and round-trip tickets from £295.

Displayed flight fares from Grand Cayman to Panama City are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight details for Grand Cayman to Panama City

The distance between Grand Cayman and Panama City is 1,164.89km. It takes around 2 hours on average to fly from Grand Cayman to Panama City. Based on Trip.com's data, travel demand peaks in July. The off-season for travel is October.

Cheapest one-way flight price£249
Cheapest return ticket price£295
Off-season travel monthOctober
Peak season for travelJuly
Flight distance1,164.89km
Average flight time2 hours
Popular airlineCayman Airways
Flight statistics for the Grand Cayman–Panama City route are based on aggregated booking data from Trip.com over the past 12 months.

Flight FAQs

  • Which airlines offer the cheapest flights from Grand Cayman (GCM) to Panama City (PTY)?

    Based on Trip.com data, Cayman Airways offers one-way fares as low as £249 on Cheapest nonstop routes (e.g. GCM to PTY on Mon, May 11), while Cayman Airways offers Cheapest nonstop round-trips from £295 departing on Thu, May 21 and returning on Thu, May 28.
  • At the moment, you can catch a direct flight from Grand Cayman to Panama City with the following airlines, including: Cayman Airways Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 2 hours to fly from Grand Cayman (GCM) to Panama City (PTY).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Grand Cayman to Panama City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 2 flight per week flying from Grand Cayman to Panama City. You can check the weekly schedule for popular airlines on this route below: Cayman Airways: S/-/-/W/-/-/- -- KX852 (12:22)
  • To find best deals on flights from Grand Cayman to Panama City, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, May 11, with one-way flights priced at just £249.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Cayman Airways.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Panama City travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Grand Cayman to Panama City is October, when demand for travel is lower.
  • After crunching the numbers on our April flight calendar, it's currently cheapest to fly from Grand Cayman to Panama City on April 23, 2026 with Cayman Airways, with prices starting at £300.
  • You can land at any one of the following hubs in Panama City, with Owen Roberts International Airport to Tocumen International Airport (GCM-PTY) is by far the most common option on this route: Marcos A. Gelabert International Airport (PAC) Tocumen International Airport (PTY).
  • The time difference between Panama City and Grand Cayman is 0h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Note: Prices shown on this page are the estimated lowest prices and include all taxes and fees found in the last 24 hours.

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Prices displayed on this page are all-inclusive (including taxes, fuel surcharges, civil aviation development fund, etc.), with all fees confirmed before payment. Fees for luggage, meals, Wi-Fi, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page have been updated within the last 24 hours—sometimes even in real time. The more popular the route, the more accurate the data.

Change & Cancellation Policy

Trip.com shows the cancellation and change policies for each flight ticket during the booking process, including any fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To request a change or cancellation, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and flight segment, and submit your request. Please note that additional charges may apply according to the airline's ticket policy.
Cancellation/change due to a flight schedule change:
If the flight schedule has changed and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please visit the customer support pages.