Cheap Flights Grand Cayman – Panama City from £249

Flight FAQs

• Which airlines offer the cheapest flights from Grand Cayman (GCM) to Panama City (PTY)?

  Based on Trip.com data, Cayman Airways offers one-way fares as low as £249 on Cheapest nonstop routes (e.g. GCM to PTY on Mon, May 11), while Cayman Airways offers Cheapest nonstop round-trips from £295 departing on Thu, May 21 and returning on Thu, May 28.

• Which airlines offer direct flights from Grand Cayman to Panama City?

  At the moment, you can catch a direct flight from Grand Cayman to Panama City with the following airlines, including: Cayman Airways Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• How long is the flight from Grand Cayman (GCM) to Panama City (PTY)?

  It takes about 2 hours to fly from Grand Cayman (GCM) to Panama City (PTY).

• When is the best time to book flights from Grand Cayman to Panama City?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Grand Cayman to Panama City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there per week from Grand Cayman to Panama City?

  Based on Trip.com data in the past 4 weeks, there is 2 flight per week flying from Grand Cayman to Panama City. You can check the weekly schedule for popular airlines on this route below: Cayman Airways: S/-/-/W/-/-/- -- KX852 (12:22)

• How can I find the best deals on flights from Grand Cayman to Panama City?

  To find best deals on flights from Grand Cayman to Panama City, you can use various tools on Trip.com:
  · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Mon, May 11, with one-way flights priced at just £249.
  · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Cayman Airways.
  · Set up price alerts to easily monitor ticket prices without having to check every day.
  · Check Trip.com flight deals and promo codes frequently.
  · Avoid peak season unless you book very early. It seems the peak season for Panama City travel is around July.
  · Get exclusive promo codes for Trip.com app users.

• When is the best time to book a flight from Grand Cayman to Panama City to get the best price?

  The cheapest months to fly from Grand Cayman to Panama City is October, when demand for travel is lower.

• Which upcoming date is the cheapest for flights from Grand Cayman to Panama City?

  After crunching the numbers on our April flight calendar, it's currently cheapest to fly from Grand Cayman to Panama City on April 23, 2026 with Cayman Airways, with prices starting at £300.

• Which airports can I fly through when travelling to Panama City from Grand Cayman?

  You can land at any one of the following hubs in Panama City, with Owen Roberts International Airport to Tocumen International Airport (GCM-PTY) is by far the most common option on this route: Marcos A. Gelabert International Airport (PAC) Tocumen International Airport (PTY).

• What is the time difference between Grand Cayman and Panama City?

  The time difference between Panama City and Grand Cayman is 0h.

• How can I change or cancel my flight ticket from Grand Cayman to Panama City?

  Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.