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Flights from Knoxville to Myrtle Beach Starting at £169

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Find the best time to fly from Knoxville to Myrtle Beach

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Airlines Flying from Knoxville to Myrtle Beach

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Frontier Airlines
From £95
United Airlines
From £172
American Airlines
From £217
Delta Air Lines
From £218
Allegiant Air
From £288
ANA airlines

Find more flights and airlines

Alternative Routes from Knoxville to Myrtle Beach

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Knoxville to Myrtle Beach.

  • Cheapest
    Frontier Airlines
    TYS
    10:56
    28h 49m
    2 transfer
    MYR
    15:45
    Mcghee Tyson Airport - Myrtle Beach International Airport
    Fri, Apr 12Frontier Airlines
    £95
  • Frontier Airlines
    TYS
    10:56
    28h 49m
    2 transfer
    MYR
    15:45
    Mcghee Tyson Airport - Myrtle Beach International Airport
    Fri, Apr 12Frontier Airlines
    £95
    Find More Flights

How do I find the cheapest flights?

  • When are flight tickets from Knoxville (TYS) to Myrtle Beach (MYR) the cheapest?

    Airlines adjust prices for flights from Knoxville to Myrtle Beach based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much are flights from Knoxville (TYS) to Myrtle Beach (MYR) cost?

    According to Trip.com's data, the lowest price is around £375.
  • What is the transportation method from the main airport to downtown in Myrtle Beach?

    • The distance from Myrtle Beach International Airport to downtown is about 3km, by taxi about 20 minutes.
  • What's the most popular airline for direct flights from Knoxville (TYS) to Myrtle Beach (MYR)?

    Allegiant Air operates 1 direct flights from Knoxville (TYS) to Myrtle Beach (MYR).
  • How many airports in Myrtle Beach (MYR)?

    There are 2 airport(s) in Myrtle Beach (MYR): Myrtle Beach Grand Strand Airport and Myrtle Beach International Airport.

Flight Information from Knoxville to Myrtle Beach

Cheapest direct flight price

£169

Cheapest month

February

Peak season for travel

October