Airlines Flying from Madrid to Santiago
Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.
Flight deals from Madrid to Santiago
We've found these cheap flights for you. You can book one-way or return flight tickets.
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Round-trip
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One way
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Cheapest nonstopMAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, Apr 29 | EuroairlinesSCU 03:058h 30mDirectMAD 17:35Santiago - Madrid | Wed, May 7 | Euroairlines£461 £64628% OFF28% OFF£646 £461
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MAD 13:309h 30mDirectSCU 17:00Madrid - Santiago | Tue, May 27 | EuroairlinesSCU 02:059h 30mDirectMAD 17:35Santiago - Madrid | Wed, Jun 4 | Euroairlines£468 £64628% OFF28% OFF£646 £468
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MAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, May 6 | EuroairlinesSCU 03:058h 30mDirectMAD 17:35Santiago - Madrid | Wed, May 7 | Euroairlines£469 £64627% OFF27% OFF£646 £469
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MAD 13:309h 30mDirectSCU 17:00Madrid - Santiago | Tue, Jun 17 | EuroairlinesSCU 02:059h 30mDirectMAD 17:35Santiago - Madrid | Wed, Jun 18 | Euroairlines£47327% OFF£646 £473
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MAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, May 13 | EuroairlinesSCU 03:058h 30mDirectMAD 17:35Santiago - Madrid | Wed, May 14 | Euroairlines£47327% OFF£646 £473
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MAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, Jun 3 | EuroairlinesSCU 03:058h 30mDirectMAD 17:35Santiago - Madrid | Wed, Jun 4 | Euroairlines£47427% OFF£646 £474
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MAD 13:309h 30mDirectSCU 17:00Madrid - Santiago | Tue, Jun 10 | EuroairlinesSCU 02:059h 30mDirectMAD 17:35Santiago - Madrid | Wed, Jun 18 | Euroairlines£48625% OFF£646 £486
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MAD 13:309h 30mDirectSCU 17:00Madrid - Santiago | Tue, May 20 | EuroairlinesSCU 02:059h 30mDirectMAD 17:35Santiago - Madrid | Wed, May 28 | Euroairlines£49623% OFF£646 £496
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MAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, Apr 29 | Cubana AirlinesSCU 03:058h 30mDirectMAD 17:35Santiago - Madrid | Wed, May 7 | Cubana Airlines£50522% OFF£646 £505
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MAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, May 6 | Cubana AirlinesSCU 03:058h 30mDirectMAD 17:35Santiago - Madrid | Wed, May 7 | Cubana Airlines£53018% OFF£646 £530
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MAD 13:0017h 25m1 stopsSCU Invalid DateMadrid - Santiago | Sun, Apr 27 | Normal AirlineSCU 15:006hDirectMAD 16:00Santiago - Madrid | Tue, Apr 29 | Normal AirlineFind More FlightsFind More Flights
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Cheapest nonstopMAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, May 20 | Cubana£315 £48735% OFF35% OFF£487 £315
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MAD 13:309h 30mDirectSCU 17:00Madrid - Santiago | Tue, Jun 10 | Euroairlines£320 £48734% OFF34% OFF£487 £320
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MAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, May 13 | Euroairlines£331 £48732% OFF32% OFF£487 £331
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MAD 13:309h 30mDirectSCU 17:00Madrid - Santiago | Tue, Jun 3 | Euroairlines£33132% OFF£487 £331
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MAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, May 20 | Euroairlines£33132% OFF£487 £331
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MAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, May 27 | Euroairlines£33132% OFF£487 £331
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MAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, Jun 17 | Euroairlines£34828% OFF£487 £348
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MAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, May 6 | Euroairlines£39020% OFF£487 £390
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MAD 13:3010h 30mDirectSCU 18:00Madrid - Santiago | Tue, May 13 | Cubana£39120% OFF£487 £391
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MAD 13:309h 30mDirectSCU 17:00Madrid - Santiago | Tue, Jun 10 | Cubana£39918% OFF£487 £399
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MAD 13:0017h 25m1 stopsSCU Invalid DateMadrid - Santiago | Sun, Apr 27 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
Flight Information from Madrid to Santiago
Cheapest one-way flight price | £283 |
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Cheapest return ticket price | £460 |
Off-season travel month | March |
Peak season for travel | January |
Flight distance | 7,109.04km |
Average flight time | 9 hours 30 minutes |
Popular airline | Aeromexico |
Find the best time to fly from Madrid to Santiago
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
FAQ
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When are flight tickets from Madrid (MAD) to Santiago (SCU) the cheapest?
Airlines adjust prices for flights from Madrid to Santiago based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much are flights from Madrid (MAD) to Santiago (SCU) cost?
According to Trip.com's data, the lowest price is around £664. -
How long is the flight from Madrid (MAD) to Santiago (SCU)?
It takes about 9 hours 30 minutes to fly from Madrid (MAD) to Santiago (SCU). -
What are the most popular airlines that fly from Madrid (MAD) to Santiago (SCU)?
Airlines with flights from Madrid (MAD) to Santiago (SCU): Euroairlines and Cubana Airlines. -
How many airports in Santiago (SCU)?
There are 1 airport(s) in Santiago (SCU): Antonio Maceo Airport.
How to find a cheap flight from Madrid to Santiago
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Madrid to Santiago. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest flight from Madrid to Santiago.
Simply tap "Date" on the flight search bar to browse through the calendar and check out airfare from Madrid to Santiago over the next 6 months in 2025. If you're planning to fly within the next three months, it looks like the most affordable option is on Tue, May 20, with one-way flights priced at just £315.
Compare cheap flight deals from Madrid to Santiago across hundreds of airlines.
With our extensive search, you can compare prices from over 500 airlines to find the cheapest flight tickets from Madrid to Santiago. The cheapest airline for this route is Cubana.
Set up a Price Alert
By setting up a Price Alert for your journey from Madrid to Santiago, you can easily keep an eye on ticket prices without having to check every day.
Don't miss out on cheap flight deals and promo codes from Madrid to Santiago.
You can always find the latest offers through Trip.com Deals and Promo Codes for cheap flights. By signing up for a free membership, you'll get access to even more deals for your flights.
Book early or wait until the last minute.
It's usually best to book early. Flight tickets are often cheapest when they're first released, typically about a year before the departure date. So, have a look online as soon as the flights you're interested in become available. If you miss the cheapest time, you might still find some good deals as the departure date gets closer.
Search for flights on the go.
For the best travel flight booking experience, download the Trip.com app. You can search for cheap flights from Madrid to Santiago and snag some exclusive deals just for you.
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