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Flights from Medellin to Cusco

Airlines operating flights from Medellin to Cusco

Choose from 2 airlines flying from Medellin to Cusco, including avianca, JetSMART Airlines and . JetSMART Airlines currently offers the cheapest ticket on this route.
Airlines are determined based on actual purchased flight tickets from Medellin to Cusco according to previous 12 months data from Trip.com.

Find the cheapest flight options from Medellin to Cusco over the next three months. Book one-way tickets from £144 and round-trip tickets from £220.

Displayed flight fares from Medellin to Cusco are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight details for Medellin to Cusco

The distance between Medellin and Cusco is 2,234.76km. Based on Trip.com's data, travel demand peaks in July. The off-season for travel is September.

Cheapest one-way flight price£144
Cheapest return ticket price£220
Off-season travel monthSeptember
Peak season for travelJuly
Flight distance2,234.76km
Popular airlineavianca
Flight statistics for the Medellin–Cusco route are based on aggregated booking data from Trip.com over the past 12 months.

Trip.com price insights on flights from Medellin to Cusco

What is the cheapest month for one-way flights from Medellin to Cusco?

The average one way ticket price paid by Trip.com users from Medellin to Cusco in each month over the past 12 months.

Based on Trip.com data, the cheapest month to fly from Medellin to Cusco is Mar, with an average price of £163. The most expensive month is usually Oct, with average prices reaching £346.

£346
£255
£163
£72
    Cheapest
  • £164
    Jan
  • £245
    Feb
  • £163
    Mar
  • £177
    Apr
  • £201
    May
  • £217
    Jun
  • £232
    Jul
  • £280
    Aug
  • £209
    Sep
  • £346
    Oct
  • £254
    Nov
  • £218
    Dec

Which day of the week is cheapest to fly from Medellin to Cusco?

Data is based on the past 12 months and shows the average weekly airfare from Medellin to Cusco on different days of the week according to Trip.com.

Based on Trip.com data from the past 12 months, the cheapest day to fly from Medellin to Cusco is Wed. The average fare on this day is usually lower than on other days. Try to avoid flying on Sat as fares are usually the highest.

£268
£233
£199
£165
    Cheapest
  • £228
    Mon
  • £247
    Tue
  • £199
    Wed
  • £211
    Thu
  • £212
    Fri
  • £267
    Sat
  • £258
    Sun

Flight FAQs

  • Which airlines offer the cheapest flights from Medellin (MDE) to Cusco (CUZ)?

    Based on Trip.com data, JetSMART Airlines offers one-way fares as low as £144 on Cheapest nonstop routes (e.g. MDE to CUZ on Sun, Feb 1), while JetSMART Airlines offers Cheapest nonstop round-trips from £220 departing on Thu, Jan 22 and returning on Thu, Jan 29.
  • At the moment, you can catch a direct flight from Medellin to Cusco with the following airlines, including: JetSMART Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Medellin to Cusco is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Medellin to Cusco, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Sun, Feb 1, with one-way flights priced at just £144.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is JetSMART Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Cusco travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Medellin to Cusco is September, when demand for travel is lower.
  • After crunching the numbers on our January flight calendar, it's currently cheapest to fly from Medellin to Cusco on January 25, 2026 with JetSMART, with prices starting at £147.
  • You can land at any one of the following hubs in Cusco, with Jose Maria Cordova International Airport to Alejandro Velasco Astete International Airport (MDE-CUZ) is by far the most common option on this route: Alejandro Velasco Astete International Airport (CUZ).
  • The time difference between Cusco and Medellin is 0h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.