Cheap Flights from New Orleans to Knoxville
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Flights from New Orleans to Knoxville
Flight deals from New Orleans to Knoxville
We've found these cheap flights for you. You can book one-way or return flight tickets.
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Round-trip
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One way
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MSY 11:533h 21m1 stopsTYS 16:14New Orleans - Knoxville | Tue, May 6 | Delta Air Lines
TYS 05:454h1 stopsMSY 08:45Knoxville - New Orleans | Tue, May 13 | Delta Air Lines£152 £25139% OFF39% OFF£251 £152 -
MSY 14:273h 47m1 stopsTYS 19:14New Orleans - Knoxville | Tue, May 6 | American Airlines
TYS 09:055h 23m1 stopsMSY 13:28Knoxville - New Orleans | Tue, May 13 | American Airlines£154 £25139% OFF39% OFF£251 £154 -
MSY 05:303h 10m1 stopsTYS 09:40New Orleans - Knoxville | Sat, Apr 5 | Delta Air Lines
TYS 05:454h 22m1 stopsMSY 09:07Knoxville - New Orleans | Sat, Apr 12 | Delta Air Lines£158 £25137% OFF37% OFF£251 £158
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MSY 05:253h 15m1 stopsTYS 09:40New Orleans - Knoxville | Wed, May 7 | Delta Air Lines
TYS 05:454h1 stopsMSY 08:45Knoxville - New Orleans | Sat, May 10 | Delta Air Lines£15837% OFF£251 £158
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MSY 17:534h 49m1 stopsTYS 23:42New Orleans - Knoxville | Sat, Apr 12 | Delta Air Lines
TYS 05:304h 39m1 stopsMSY 09:09Knoxville - New Orleans | Tue, Apr 15 | Delta Air Lines£15937% OFF£251 £159
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MSY 14:233h 45m1 stopsTYS 19:08New Orleans - Knoxville | Sat, Apr 12 | American Airlines
TYS 13:005h 51m1 stopsMSY 17:51Knoxville - New Orleans | Sat, Apr 19 | American Airlines£16036% OFF£251 £160
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MSY 06:306h 10m1 stopsTYS 13:40New Orleans - Knoxville | Wed, Apr 2 | Delta Air Lines
TYS 05:456h1 stopsMSY 10:45Knoxville - New Orleans | Wed, Apr 9 | Delta Air Lines£16136% OFF£251 £161
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MSY 10:503h 27m1 stopsTYS 15:17New Orleans - Knoxville | Fri, May 9 | Delta Air Lines
TYS 14:206h 10m1 stopsMSY 19:30Knoxville - New Orleans | Sat, May 10 | Delta Air Lines£17032% OFF£251 £170
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MSY 05:253h 15m1 stopsTYS 09:40New Orleans - Knoxville | Fri, May 23 | Delta Air Lines
TYS 05:455h1 stopsMSY 09:45Knoxville - New Orleans | Tue, May 27 | Delta Air Lines£17032% OFF£251 £170
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MSY 07:455h 3m1 stopsTYS 13:48New Orleans - Knoxville | Fri, Apr 18 | Delta Air Lines
TYS 05:304h 39m1 stopsMSY 09:09Knoxville - New Orleans | Sun, Apr 20 | Delta Air Lines£17828% OFF£251 £178
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MSY 13:0017h 25m1 stopsTYS Invalid DateNew Orleans - Knoxville | Tue, Apr 1 | Normal Airline
TYS 15:006hNonstopMSY 16:00Knoxville - New Orleans | Thu, Apr 3 | Normal AirlineFind More FlightsFind More Flights
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MSY 05:303h 10m1 stopsTYS 09:40New Orleans - Knoxville | Sat, Apr 5 | Delta Air Lines£82 £21762% OFF62% OFF£217 £82
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MSY 07:305h 20m1 stopsTYS 13:50New Orleans - Knoxville | Wed, Apr 9 | Delta Air Lines£82 £21762% OFF62% OFF£217 £82
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MSY 19:4714h 59m1 stopsTYS 11:46New Orleans - Knoxville | Thu, Apr 17 | Frontier Airlines£86 £21760% OFF60% OFF£217 £86 -
MSY 08:005h 40m1 stopsTYS 14:40New Orleans - Knoxville | Wed, Apr 16 | United Airlines£9755% OFF£217 £97 -
MSY 07:005h 22m1 stopsTYS 13:22New Orleans - Knoxville | Sat, Apr 5 | United Airlines£10153% OFF£217 £101
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MSY 08:005h 40m1 stopsTYS 14:40New Orleans - Knoxville | Wed, Apr 30 | United Airlines£10153% OFF£217 £101
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MSY 12:594h 35m1 stopsTYS 18:34New Orleans - Knoxville | Wed, Apr 2 | Delta Air Lines£13338% OFF£217 £133
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MSY 07:005h 22m1 stopsTYS 13:22New Orleans - Knoxville | Wed, Apr 9 | United Airlines£15130% OFF£217 £151
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MSY 19:143h 23m1 stopsTYS 23:37New Orleans - Knoxville | Mon, Mar 31 | Delta Air Lines£15230% OFF£217 £152
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MSY 05:304h 45m1 stopsTYS 11:15New Orleans - Knoxville | Mon, Apr 7 | Delta Air Lines£15428% OFF£217 £154
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MSY 13:0017h 25m1 stopsTYS Invalid DateNew Orleans - Knoxville | Tue, Apr 1 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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FAQ
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When are flight tickets from New Orleans (MSY) to Knoxville (TYS) the cheapest?
Airlines adjust prices for flights from New Orleans to Knoxville based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much are flights from New Orleans (MSY) to Knoxville (TYS) cost?
According to Trip.com's data, the lowest price is around £312. -
How many airports in Knoxville (TYS)?
There are 1 airport(s) in Knoxville (TYS): Mcghee Tyson Airport.
How to find a cheap flight from New Orleans to Knoxville
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from New Orleans to Knoxville. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest flight from New Orleans to Knoxville.
Simply tap "Date" on the flight search bar to browse through the calendar and check out airfare from New Orleans to Knoxville over the next 6 months in 2025. If you're planning to fly within the next three months, it looks like the most affordable option is on Sat, Apr 5, with one-way flights priced at just £82.
Compare cheap flight deals from New Orleans to Knoxville across hundreds of airlines.
With our extensive search, you can compare prices from over 500 airlines to find the cheapest flight tickets from New Orleans to Knoxville. The cheapest airline for this route is Delta Air Lines.
Set up a Price Alert
By setting up a Price Alert for your journey from New Orleans to Knoxville, you can easily keep an eye on ticket prices without having to check every day.
Don't miss out on cheap flight deals and promo codes from New Orleans to Knoxville.
You can always find the latest offers through Trip.com Deals and Promo Codes for cheap flights. By signing up for a free membership, you'll get access to even more deals for your flights.
Book early or wait until the last minute.
It's usually best to book early. Flight tickets are often cheapest when they're first released, typically about a year before the departure date. So, have a look online as soon as the flights you're interested in become available. If you miss the cheapest time, you might still find some good deals as the departure date gets closer.
Search for flights on the go.
For the best travel flight booking experience, download the Trip.com app. You can search for cheap flights from New Orleans to Knoxville and snag some exclusive deals just for you.
Flight Information from New Orleans to Knoxville
| Cheapest one-way flight price | £81 |
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| Off-season travel month | March |
| Peak season for travel | May |
| Flight distance | 863.47km |
| Popular airline | American Airlines |
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