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Flights from Panama City to Guatemala City

Airlines operating flights from Panama City to Guatemala City

Choose from 1 airlines flying from Panama City to Guatemala City, including Copa Airlines, and . Copa Airlines currently offers the cheapest ticket on this route.
Copa Airlines logo Copa Airlines
Airlines are determined based on actual purchased flight tickets from Panama City to Guatemala City according to previous 12 months data from Trip.com.

Find the cheapest direct flight options from Panama City to Guatemala City over the next three months. Book one-way tickets from £104 and round-trip tickets from £152.

      • Cheapest nonstop
        PTY 08:11
        2h 23m
        Direct
        GUA 09:34
        Panama City - Guatemala City | Sun, Feb 1 | Copa Airlines
        GUA 04:24
        2h 26m
        Direct
        PTY 07:50
        Guatemala City - Panama City | Sat, Feb 7 | Copa Airlines
        £152 £214
        28% off
        28% off
        £214 £152
      • PTY 07:31
        2h 24m
        Direct
        GUA 08:55
        Panama City - Guatemala City | Sat, Feb 7 | Copa Airlines
        GUA 04:24
        2h 26m
        Direct
        PTY 07:50
        Guatemala City - Panama City | Sun, Feb 8 | Copa Airlines
        £152 £214
        28% off
        28% off
        £214 £152
      • PTY 17:50
        8h 50m
        1 stop
        GUA 01:40
        Panama City - Guatemala City | Fri, Jan 30 | avianca
        GUA 13:55
        10h 5m
        1 stop
        PTY 01:00
        Guatemala City - Panama City | Sat, Feb 7 | avianca
        £143 £214
        33% off
        33% off
        £214 £143
      • PTY 02:55
        11h 5m
        1 stop
        GUA 13:00
        Panama City - Guatemala City | Wed, Feb 11 | avianca
        GUA 06:20
        9h 35m
        1 stop
        PTY 16:55
        Guatemala City - Panama City | Thu, Feb 19 | avianca
        £143
        33% off
        £214 £143
      • PTY 14:55
        11h 45m
        1 stop
        GUA 01:40
        Panama City - Guatemala City | Mon, Feb 2 | avianca
        GUA 06:20
        6h 40m
        1 stop
        PTY 14:00
        Guatemala City - Panama City | Sat, Feb 7 | avianca
        £143
        33% off
        £214 £143
      • PTY 02:55
        11h 5m
        1 stop
        GUA 13:00
        Panama City - Guatemala City | Thu, Feb 5 | avianca
        GUA 06:20
        6h 40m
        1 stop
        PTY 14:00
        Guatemala City - Panama City | Sat, Feb 7 | avianca
        £147
        31% off
        £214 £147
      • PTY 14:55
        11h 45m
        1 stop
        GUA 01:40
        Panama City - Guatemala City | Fri, Feb 13 | avianca
        GUA 09:30
        14h 10m
        1 stop
        PTY 00:40
        Guatemala City - Panama City | Fri, Feb 20 | avianca
        £148
        31% off
        £214 £148
      • PTY 09:45
        8h 55m
        1 stop
        GUA 17:40
        Panama City - Guatemala City | Tue, Jan 20 | avianca
        GUA 09:30
        6h 25m
        1 stop
        PTY 16:55
        Guatemala City - Panama City | Fri, Jan 23 | avianca
        £148
        31% off
        £214 £148
      • PTY 02:55
        15h 45m
        1 stop
        GUA 17:40
        Panama City - Guatemala City | Sun, Feb 1 | avianca
        GUA 06:20
        6h 40m
        1 stop
        PTY 14:00
        Guatemala City - Panama City | Sat, Feb 7 | avianca
        £148
        31% off
        £214 £148
      • PTY 14:55
        11h 45m
        1 stop
        GUA 01:40
        Panama City - Guatemala City | Mon, Feb 23 | avianca
        GUA 09:30
        6h 25m
        1 stop
        PTY 16:55
        Guatemala City - Panama City | Sun, Mar 1 | avianca
        £148
        31% off
        £214 £148
      • PTY 09:45
        8h 55m
        1 stop
        GUA 17:40
        Panama City - Guatemala City | Thu, Feb 12 | avianca
        GUA 06:20
        6h 40m
        1 stop
        PTY 14:00
        Guatemala City - Panama City | Thu, Feb 19 | avianca
        £148
        31% off
        £214 £148
      • PTY 09:45
        8h 55m
        1 stop
        GUA 17:40
        Panama City - Guatemala City | Wed, Jan 28 | avianca
        GUA 13:55
        10h 5m
        1 stop
        PTY 01:00
        Guatemala City - Panama City | Thu, Feb 5 | avianca
        £148
        31% off
        £214 £148
      • PTY 13:00
        17h 25m
        1 stop
        GUA Invalid Date
        Panama City - Guatemala City | Tue, Jan 20 | Normal Airline
        GUA 15:00
        6h
        Direct
        PTY 16:00
        Guatemala City - Panama City | Thu, Jan 22 | Normal Airline
        Find more flights
        Find more flights
      • Cheapest nonstop
        PTY 08:11
        2h 23m
        Direct
        GUA 09:34
        Panama City - Guatemala City | Sun, Mar 1 | Copa Airlines
        £104 £147
        28% off
        28% off
        £147 £104
      • PTY 18:34
        4h 6m
        Direct
        GUA 21:40
        Panama City - Guatemala City | Wed, Feb 4 | Copa Airlines
        £105 £147
        28% off
        28% off
        £147 £105
      • PTY 09:45
        16h 55m
        1 stop
        GUA 01:40
        Panama City - Guatemala City | Wed, Feb 11 | avianca
        £99 £147
        33% off
        33% off
        £147 £99
      • PTY 09:45
        16h 55m
        1 stop
        GUA 01:40
        Panama City - Guatemala City | Wed, Feb 4 | avianca
        £99
        33% off
        £147 £99
      • PTY 09:45
        16h 55m
        1 stop
        GUA 01:40
        Panama City - Guatemala City | Fri, Jan 23 | avianca
        £99
        33% off
        £147 £99
      • PTY 02:55
        11h 5m
        1 stop
        GUA 13:00
        Panama City - Guatemala City | Sat, Jan 24 | avianca
        £99
        33% off
        £147 £99
      • PTY 02:55
        11h 5m
        1 stop
        GUA 13:00
        Panama City - Guatemala City | Tue, Feb 17 | avianca
        £100
        32% off
        £147 £100
      • PTY 09:45
        16h 55m
        1 stop
        GUA 01:40
        Panama City - Guatemala City | Mon, Mar 9 | avianca
        £100
        32% off
        £147 £100
      • PTY 02:55
        11h 5m
        1 stop
        GUA 13:00
        Panama City - Guatemala City | Tue, Feb 10 | avianca
        £100
        32% off
        £147 £100
      • PTY 09:45
        16h 55m
        1 stop
        GUA 01:40
        Panama City - Guatemala City | Mon, Feb 9 | avianca
        £100
        32% off
        £147 £100
      • PTY 09:45
        16h 55m
        1 stop
        GUA 01:40
        Panama City - Guatemala City | Sun, Mar 15 | avianca
        £100
        32% off
        £147 £100
      • PTY 09:45
        16h 55m
        1 stop
        GUA 01:40
        Panama City - Guatemala City | Fri, Mar 6 | avianca
        £100
        32% off
        £147 £100
      • PTY 13:00
        17h 25m
        1 stop
        GUA Invalid Date
        Panama City - Guatemala City | Tue, Jan 20 | Normal Airline
        Find more flights
        Find more flights

Displayed flight fares from Panama City to Guatemala City are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight details for Panama City to Guatemala City

The distance between Panama City and Guatemala City is 1,349.41km. It takes around 2 hours 39 minutes on average to fly from Panama City to Guatemala City. Based on Trip.com's data, travel demand peaks in January. The off-season for travel is November.

Cheapest one-way flight price£99
Cheapest return ticket price£143
Off-season travel monthNovember
Peak season for travelJanuary
Flight distance1,349.41km
Average flight time2 hours 39 minutes
Popular airlineCopa Airlines
Flight statistics for the Panama City–Guatemala City route are based on aggregated booking data from Trip.com over the past 12 months.

Trip.com price insights on flights from Panama City to Guatemala City

What is the cheapest month for one-way flights from Panama City to Guatemala City?

The average one way ticket price paid by Trip.com users from Panama City to Guatemala City in each month over the past 12 months.

Based on Trip.com data, the cheapest month to fly from Panama City to Guatemala City is Mar, with an average price of £121. The most expensive month is usually Jul, with average prices reaching £228.

£228
£175
£121
£68
    Cheapest
  • £179
    Jan
  • £165
    Feb
  • £121
    Mar
  • £149
    Apr
  • £199
    May
  • £127
    Jun
  • £228
    Jul
  • £181
    Aug
  • £200
    Sep
  • £199
    Oct
  • £192
    Nov
  • £186
    Dec

Which day of the week is cheapest to fly from Panama City to Guatemala City?

Data is based on the past 12 months and shows the average weekly airfare from Panama City to Guatemala City on different days of the week according to Trip.com.

Based on Trip.com data from the past 12 months, the cheapest day to fly from Panama City to Guatemala City is Wed. The average fare on this day is usually lower than on other days. Try to avoid flying on Thu as fares are usually the highest.

£237
£191
£145
£99
    Cheapest
  • £184
    Mon
  • £165
    Tue
  • £144
    Wed
  • £237
    Thu
  • £184
    Fri
  • £195
    Sat
  • £212
    Sun

Flight FAQs

  • Which airlines offer the cheapest flights from Panama City (PTY) to Guatemala City (GUA)?

    Based on Trip.com data, avianca offers one-way fares as low as £99 on Cheapest nonstop routes (e.g. PTY to GUA on Wed, Feb 11), while avianca offers Cheapest nonstop round-trips from £143 departing on Fri, Jan 30 and returning on Sat, Feb 7.
  • At the moment, you can catch a direct flight from Panama City to Guatemala City with the following airlines, including: Copa Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 2 hours 39 minutes to fly from Panama City (PTY) to Guatemala City (GUA).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Panama City to Guatemala City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 43 flight per week flying from Panama City to Guatemala City. You can check the weekly schedule for popular airlines on this route below: Copa Airlines: S/M/T/W/T/F/S -- CM102 (08:25) Copa Airlines: S/M/T/W/T/F/S -- CM380 (07:47)
  • To find best deals on flights from Panama City to Guatemala City, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Wed, Feb 11, with one-way flights priced at just £99.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Copa Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Guatemala City travel is around January.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Panama City to Guatemala City is November, when demand for travel is lower.
  • After crunching the numbers on our January flight calendar, it's currently cheapest to fly from Panama City to Guatemala City on January 20, 2026 with avianca, with prices starting at £68.
  • You can land at any one of the following hubs in Guatemala City, with Tocumen International Airport to La Aurora International Airport (PTY-GUA) is by far the most common option on this route: La Aurora International Airport (GUA).
  • The time difference between Guatemala City and Panama City is 1h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

More Flight Itineraries