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Latest Flight Deals from Panama City to Madrid

Book one-way or return flights from Panama City to Madrid from as little as £270. Choose from the popular airlines below and book your flight today!

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from Panama City to Madrid? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from Panama City to Madrid. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Airlines Flying from Panama City to Madrid

View airlines operating flights from Panama City to Madrid. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Avianca
From £270
Air Europa
From £313
Iberia
From £329
United Airlines
From £430
Copa Airlines
From £449
Air Canada
From £453
Turkish Airlines
From £479
American Airlines
From £510
Air France
From £535
KLM Royal Dutch Airlines
From £554
ANA airlines

Find more flights and airlines

Alternative Routes from Panama City to Madrid

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Panama City to Madrid.

  • Cheapest
    Avianca
    PTY
    15:40
    19h 30m
    1 transfer
    MAD
    18:10
    Tocumen International Airport - Madrid Barajas Airport
    Tue, Jun 25Avianca
    £270
  • Avianca
    PTY
    15:40
    19h 30m
    1 transfer
    MAD
    18:10
    Tocumen International Airport - Madrid Barajas Airport
    Tue, Jun 25Avianca
    £270
    Find More Flights

How do I find the cheapest flights?

  • When are flight tickets from Panama City (PTY) to Madrid (MAD) the cheapest?

    Airlines adjust prices for flights from Panama City to Madrid based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much are flights from Panama City (PTY) to Madrid (MAD) cost?

    According to Trip.com's data, the lowest price is around £723.
  • How long is the flight from Panama City (PTY) to Madrid (MAD)?

    It takes about 10 hours 4 minutes to fly from Panama City (PTY) to Madrid (MAD).
  • What is the transportation method from the main airport to downtown in Madrid?

    • The distance from Madrid Barajas Airport to downtown is about 14km, by taxi about 30 minutes.
  • What are the most popular airlines that fly from Panama City (PTY) to Madrid (MAD)?

    Airlines with flights from Panama City (PTY) to Madrid (MAD): Copa Airlines, Qatar Airways, El Al, British Airways, Iberia and Air Europa.
  • What's the most popular airline for direct flights from Panama City (PTY) to Madrid (MAD)?

    Iberia operates 1 direct flights from Panama City (PTY) to Madrid (MAD).
  • How many airports in Madrid (MAD)?

    There are 2 airport(s) in Madrid (MAD): Madrid Barajas Airport and Madrid Torrejon.

How to find a cheap flight from Panama City to Madrid

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Panama City to Madrid. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com
Flight Information from Panama City to Madrid

Cheapest direct flight price

£269

Cheapest return ticket price

£489

Cheapest month

February

Peak season for travel

October

Flight distance

8,177.05km

Average flight time

10 hours 4 minutes

Popular airline

Avianca