Airlines operating flights from Panama City to Medellin
Copa Airlines Flight deals from Panama City to Medellin
Find the cheapest direct flight options from Panama City to Medellin over the next three months. Book one-way tickets from £95 and round-trip tickets from £176.
- Return
- One way
-
- Cheapest nonstop
PTY 08:281h 23mDirectMDE 09:51Panama City - Medellin | Mon, Feb 23 | Copa Airlines
MDE 10:461h 28mDirectPTY 12:14Medellin - Panama City | Sun, Mar 1 | Copa Airlines£176 £23324% off24% off£233 £176 -
PTY 07:001h 18mDirectMDE 08:18Panama City - Medellin | Sat, Feb 21 | Copa Airlines
MDE 12:421h 28mDirectPTY 14:10Medellin - Panama City | Thu, Feb 26 | Copa Airlines£177 £23324% off24% off£233 £177 -
PTY 02:554h 10m1 stopMDE 07:05Panama City - Medellin | Sun, Mar 1 | avianca
MDE 04:204h 30m1 stopPTY 08:50Medellin - Panama City | Tue, Mar 3 | avianca£163 £23330% off30% off£233 £163 -
PTY 02:554h 10m1 stopMDE 07:05Panama City - Medellin | Fri, Feb 13 | avianca
MDE 11:555h1 stopPTY 16:55Medellin - Panama City | Tue, Feb 17 | avianca£16330% off£233 £163 -
PTY 02:554h 50m1 stopMDE 07:45Panama City - Medellin | Mon, Feb 23 | avianca
MDE 08:305h 30m1 stopPTY 14:00Medellin - Panama City | Sun, Mar 1 | avianca£16330% off£233 £163 -
PTY 14:554h1 stopMDE 18:55Panama City - Medellin | Sat, Feb 21 | avianca
MDE 20:104h 30m1 stopPTY 00:40Medellin - Panama City | Mon, Feb 23 | avianca£16430% off£233 £164 -
PTY 02:554h 10m1 stopMDE 07:05Panama City - Medellin | Sat, Feb 28 | avianca
MDE 11:405h 15m1 stopPTY 16:55Medellin - Panama City | Sat, Mar 7 | avianca£16728% off£233 £167 -
PTY 14:555h 20m1 stopMDE 20:15Panama City - Medellin | Mon, Feb 16 | avianca
MDE 11:405h 15m1 stopPTY 16:55Medellin - Panama City | Fri, Feb 20 | avianca£16828% off£233 £168 -
PTY 02:554h 10m1 stopMDE 07:05Panama City - Medellin | Fri, Feb 27 | avianca
MDE 19:555h 5m1 stopPTY 01:00Medellin - Panama City | Sat, Feb 28 | avianca£16828% off£233 £168 -
PTY 02:554h 10m1 stopMDE 07:05Panama City - Medellin | Wed, Feb 18 | avianca
MDE 19:405h 20m1 stopPTY 01:00Medellin - Panama City | Sun, Feb 22 | avianca£16828% off£233 £168 -
PTY 02:554h 10m1 stopMDE 07:05Panama City - Medellin | Fri, Mar 6 | avianca
MDE 08:305h 30m1 stopPTY 14:00Medellin - Panama City | Sun, Mar 8 | avianca£16828% off£233 £168 -
PTY 02:554h 10m1 stopMDE 07:05Panama City - Medellin | Thu, Feb 12 | avianca
MDE 09:504h 10m1 stopPTY 14:00Medellin - Panama City | Sun, Feb 15 | avianca£16927% off£233 £169 -
PTY 13:0017h 25m1 stopMDE Invalid DatePanama City - Medellin | Sat, Feb 14 | Normal Airline
MDE 15:006hDirectPTY 16:00Medellin - Panama City | Mon, Feb 16 | Normal AirlineFind more flightsFind more flights
-
Cheapest nonstop
PTY 07:001h 18mDirectMDE 08:18Panama City - Medellin | Thu, Feb 12 | Copa Airlines£95 £14534% off34% off£145 £95 -
PTY 08:281h 23mDirectMDE 09:51Panama City - Medellin | Wed, Mar 11 | Copa Airlines£96 £14534% off34% off£145 £96 -
PTY 07:001h 18mDirectMDE 08:18Panama City - Medellin | Sat, Feb 14 | Copa Airlines£108 £14526% off26% off£145 £108 -
PTY 07:001h 18mDirectMDE 08:18Panama City - Medellin | Sat, Mar 14 | Copa Airlines£11024% off£145 £110 -
PTY 02:554h 50m1 stopMDE 07:45Panama City - Medellin | Thu, Feb 12 | avianca£8839% off£145 £88 -
PTY 14:554h 35m1 stopMDE 19:30Panama City - Medellin | Sun, Mar 8 | avianca£8939% off£145 £89 -
PTY 02:554h 50m1 stopMDE 07:45Panama City - Medellin | Sat, Mar 14 | avianca£9137% off£145 £91 -
PTY 02:554h 50m1 stopMDE 07:45Panama City - Medellin | Wed, Mar 11 | avianca£9336% off£145 £93 -
PTY 02:556h 10m1 stopMDE 09:05Panama City - Medellin | Mon, Feb 23 | avianca£10130% off£145 £101 -
PTY 02:554h 50m1 stopMDE 07:45Panama City - Medellin | Sun, Feb 22 | avianca£10230% off£145 £102 -
PTY 13:0017h 25m1 stopMDE Invalid DatePanama City - Medellin | Sat, Feb 14 | Normal AirlineFind more flightsFind more flights
Displayed flight fares from Panama City to Medellin are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.
Flight details for Panama City to Medellin
The distance between Panama City and Medellin is 530.92km. It takes around 1 hour 24 minutes on average to fly from Panama City to Medellin. Based on Trip.com's data, travel demand peaks in September. The off-season for travel is November.
| Cheapest one-way flight price | £88 |
|---|---|
| Cheapest return ticket price | £163 |
| Off-season travel month | November |
| Peak season for travel | September |
| Flight distance | 530.92km |
| Average flight time | 1 hour 24 minutes |
| Popular airline | Copa Airlines |
Trip.com price insights on flights from Panama City to Medellin
What is the cheapest month for one-way flights from Panama City to Medellin?
Based on Trip.com data, the cheapest month to fly from Panama City to Medellin is Apr, with an average price of £113. The most expensive month is usually Dec, with average prices reaching £172.
Which day of the week is cheapest to fly from Panama City to Medellin?
Based on Trip.com data from the past 12 months, the cheapest day to fly from Panama City to Medellin is Wed. The average fare on this day is usually lower than on other days. Try to avoid flying on Mon as fares are usually the highest.
Flight FAQs
Which airlines offer the cheapest flights from Panama City (PTY) to Medellin (MDE)?
Based on Trip.com data, avianca offers one-way fares as low as £88 on Cheapest nonstop routes (e.g. PTY to MDE on Thu, Feb 12), while avianca offers Cheapest nonstop round-trips from £163 departing on Sun, Mar 1 and returning on Tue, Mar 3.Which airlines offer direct flights from Panama City to Medellin?
At the moment, you can catch a direct flight from Panama City to Medellin with the following airlines, including: Copa Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.How long is the flight from Panama City (PTY) to Medellin (MDE)?
It takes about 1 hour 24 minutes to fly from Panama City (PTY) to Medellin (MDE).When is the best time to book flights from Panama City to Medellin?
By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Panama City to Medellin is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.How many flights are there per week from Panama City to Medellin?
Based on Trip.com data in the past 4 weeks, there is 48 flight per week flying from Panama City to Medellin. You can check the weekly schedule for popular airlines on this route below: Copa Airlines: S/M/T/W/T/F/S -- CM397 (09:34) Copa Airlines: S/M/T/W/T/F/S -- CM150 (07:12)How can I find the best deals on flights from Panama City to Medellin?
To find best deals on flights from Panama City to Medellin, you can use various tools on Trip.com:
· Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Feb 12, with one-way flights priced at just £88.
· Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Copa Airlines.
· Set up price alerts to easily monitor ticket prices without having to check every day.
· Check Trip.com flight deals and promo codes frequently.
· Avoid peak season unless you book very early. It seems the peak season for Medellin travel is around September.
· Get exclusive promo codes for Trip.com app users.When is the best time to book a flight from Panama City to Medellin to get the best price?
The cheapest months to fly from Panama City to Medellin is November, when demand for travel is lower.Which upcoming date is the cheapest for flights from Panama City to Medellin?
After crunching the numbers on our February flight calendar, it's currently cheapest to fly from Panama City to Medellin on February 25, 2026 with avianca, with prices starting at £89.Which airports can I fly through when travelling to Medellin from Panama City?
You can land at any one of the following hubs in Medellin, with Tocumen International Airport to Jose Maria Cordova International Airport (PTY-MDE) is by far the most common option on this route: Olaya Herrera Airport (EOH) Jose Maria Cordova International Airport (MDE).What is the time difference between Panama City and Medellin?
The time difference between Medellin and Panama City is 0h.How can I change or cancel my flight ticket from Panama City to Medellin?
Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.
Trip.com airline insights on flights from Panama City to Medellin
Which airlines operate the most flights from Panama City to Medellin?
According to Trip.com data from the past month, the airline with the most flights from Panama City to Medellin is Copa Airlines, operating 63 flights per week.
How many flights fly from Panama City to Medellin each day?
Based on Trip.com data from the past month, flights from Panama City to Medellin are most frequent on Friday, while the fewest flights operate on Thursday.
More Flight Itineraries
- Flights from Panama City to London
- Flights from Panama City to Bogota
- Cheap flights from Panama City to David
- Panama City to Manchester plane tickets
- Flights from Panama City to San Jose
- Panama City to Mexico City plane tickets
- Cheap flights from Panama City to Cartagena
- Panama City to Miami plane tickets
- Flights from Panama City to Guatemala City
- Flights from Panama City to Medellin
- Flights from Pereira to Medellin
- Cheap flights from Bogota to Medellin
- Cancun to Medellin plane tickets
- Cheap flights from Cartagena to Medellin
- Flights from Santa Marta to Medellin
- Flights from Lima to Medellin
- Cheap flights from Cali to Medellin
- Flights from Madrid to Medellin
- Flights from Panama City to Medellin
- Cheap flights from London to Medellin