Cheap Flights Panama City – Medellin from £88

Flight FAQs

• Which airlines offer the cheapest flights from Panama City (PTY) to Medellin (MDE)?

  Based on Trip.com data, avianca offers one-way fares as low as £88 on Cheapest nonstop routes (e.g. PTY to MDE on Thu, Feb 12), while avianca offers Cheapest nonstop round-trips from £163 departing on Sun, Mar 1 and returning on Tue, Mar 3.

• Which airlines offer direct flights from Panama City to Medellin?

  At the moment, you can catch a direct flight from Panama City to Medellin with the following airlines, including: Copa Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• How long is the flight from Panama City (PTY) to Medellin (MDE)?

  It takes about 1 hour 24 minutes to fly from Panama City (PTY) to Medellin (MDE).

• When is the best time to book flights from Panama City to Medellin?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Panama City to Medellin is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there per week from Panama City to Medellin?

  Based on Trip.com data in the past 4 weeks, there is 48 flight per week flying from Panama City to Medellin. You can check the weekly schedule for popular airlines on this route below: Copa Airlines: S/M/T/W/T/F/S -- CM397 (09:34) Copa Airlines: S/M/T/W/T/F/S -- CM150 (07:12)

• How can I find the best deals on flights from Panama City to Medellin?

  To find best deals on flights from Panama City to Medellin, you can use various tools on Trip.com:
  · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Feb 12, with one-way flights priced at just £88.
  · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Copa Airlines.
  · Set up price alerts to easily monitor ticket prices without having to check every day.
  · Check Trip.com flight deals and promo codes frequently.
  · Avoid peak season unless you book very early. It seems the peak season for Medellin travel is around September.
  · Get exclusive promo codes for Trip.com app users.

• When is the best time to book a flight from Panama City to Medellin to get the best price?

  The cheapest months to fly from Panama City to Medellin is November, when demand for travel is lower.

• Which upcoming date is the cheapest for flights from Panama City to Medellin?

  After crunching the numbers on our February flight calendar, it's currently cheapest to fly from Panama City to Medellin on February 25, 2026 with avianca, with prices starting at £89.

• Which airports can I fly through when travelling to Medellin from Panama City?

  You can land at any one of the following hubs in Medellin, with Tocumen International Airport to Jose Maria Cordova International Airport (PTY-MDE) is by far the most common option on this route: Olaya Herrera Airport (EOH) Jose Maria Cordova International Airport (MDE).

• What is the time difference between Panama City and Medellin?

  The time difference between Medellin and Panama City is 0h.

• How can I change or cancel my flight ticket from Panama City to Medellin?

  Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.