Flight deals from Panama City to Santa Cruz

We've found these cheap flights for you. You can book one-way or return flight tickets.

Round-trip
One way

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Find the best time to fly from Panama City to Santa Cruz

We monitor flight fares to help you find the best deals effortlessly

Cheapest flights

From price

20 27
May

27 4
4 11
11 18
18 25
Jun

25 1
1 8
8 15
15 22
22 29
Jul

29 6
6 13

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

When are flight tickets from Panama City (ECP) to Santa Cruz (SRZ) the cheapest?

Airlines adjust prices for flights from Panama City to Santa Cruz based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much are flights from Panama City (ECP) to Santa Cruz (SRZ) cost?

According to Trip.com's data, the lowest price is around £635.
How many airports in Santa Cruz (SRZ)?

There are 1 airport(s) in Santa Cruz (SRZ): Viru Viru International Airport.

How to find a cheap flight from Panama City to Santa Cruz

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Panama City to Santa Cruz. Book your flights at the right time and save more.

Be flexible with your travel dates to get the cheapest flight from Panama City to Santa Cruz.

Tap "Date" on the flight search bar to browse the calendar for Panama City to Santa Cruz airfare over the next 6 months in 2025.

Compare cheap flight deals from Panama City to Santa Cruz across hundreds of airlines.

Use our comprehensive search to compare fares from over 500 airlines and find the most affordable flight tickets from Panama City to Santa Cruz.

Set up a Price Alert

By setting up a Price Alert for your journey from Panama City to Santa Cruz, you can easily keep an eye on ticket prices without having to check every day.

Don't miss out on cheap flight deals and promo codes from Panama City to Santa Cruz.

You can always find the latest offers through Trip.com Deals and Promo Codes for cheap flights. By signing up for a free membership, you'll get access to even more deals for your flights.

Book early or wait until the last minute.

It's usually best to book early. Flight tickets are often cheapest when they're first released, typically about a year before the departure date. So, have a look online as soon as the flights you're interested in become available. If you miss the cheapest time, you might still find some good deals as the departure date gets closer.

Search for flights on the go.

For the best travel flight booking experience, download the Trip.com app. You can search for cheap flights from Panama City to Santa Cruz and snag some exclusive deals just for you.