> > > >
Flights from Santiago to Cusco

Airlines operating flights from Santiago to Cusco

Choose from 3 carriers that fly from Santiago to Cusco, including LATAM Airlines, Sky Airline, and JetSMART. Enjoy the cheapest tickets on this route with LATAM Airlines.

Find direct flights from Santiago to Cusco within the next three months. Book one-way flights from £86 or return tickets from £205.

Displayed flight fares from Santiago to Cusco are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight details for Santiago to Cusco

The distance between Santiago and Cusco is about 2,211.1km. It takes around 4 hours 30 minutes on average to fly from Santiago to Cusco. The most popular month to Cusco is July. The off-season for travel is November.

Cheapest one-way flight price£84
Cheapest return ticket price£136
Off-season travel monthNovember
Peak season for travelJuly
Flight distance2,211.1km
Average flight time4 hours 30 minutes
Popular airlineLATAM Airlines

Find the best time to fly from Santiago to Cusco

The cheapest time for Santiago to Cusco flights: Jan 18 to Jan 25 — one way flight prices from £84.

Cheapest flights
From price
Search
  • Dec

    307
  • 714
  • 1421
  • 2128
  • Jan

    284
  • 411
  • 1118
  • 1825
  • Feb

    251
  • 18
  • 815
  • 1522
Displayed fare trends are based on Trip.com's aggregated average of the lowest flight prices from Santiago to Cusco, calculated over the upcoming 10 weeks.

Flight FAQs

  • Which airlines offer the cheapest flights from Santiago (SCL) to Cusco (CUZ)?

    Based on Trip.com data, LATAM Airlines offers one-way fares as low as £84 on Cheapest nonstop routes (e.g. SCL to CUZ on Tue, Jan 20), while JetSMART Airlines offers Cheapest nonstop round-trips from £136 departing on Mon, Dec 8 and returning on Mon, Dec 15.
  • At the moment, you can catch a direct flight from Santiago to Cusco with the following airlines, including: LATAM Airlines Sky Airline Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 4 hours 30 minutes to fly from Santiago (SCL) to Cusco (CUZ).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santiago to Cusco is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 7 flight per week flying from Santiago to Cusco. You can check the weekly schedule for popular airlines on this route below: LATAM Airlines: S/M/T/W/T/F/S -- LA2367 (15:56) LATAM Airlines: -/-/-/-/-/-/- -- LA2467 (20:59)
  • To find best deals on flights from Santiago to Cusco, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Tue, Jan 20, with one-way flights priced at just £84.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is LATAM Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Cusco travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Santiago to Cusco is November, when demand for travel is lower.
  • After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Santiago to Cusco on December 13, 2025 with JetSMART, with prices starting at £73.
  • You can land at any one of the following hubs in Cusco, with Arturo Merino Benitez International Airport to Alejandro Velasco Astete International Airport (SCL-CUZ) is by far the most common option on this route: Alejandro Velasco Astete International Airport (CUZ).
  • The time difference between Cusco and Santiago is 1h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.