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Flights from Southampton to Brussels

Airlines Flying from Southampton to Brussels

Choose from 0 carriers that fly from Southampton to Brussels, including , Enjoy the cheapest tickets on this route with Aer Lingus.

Find the cheapest flights from Southampton to Brussels within the next three months. Book one-way flights from £50 or return tickets from £162.

      • SOU 20:10
        12h 25m
        1 stop
        BRU 09:35
        Southampton - Brussels | Tue, Nov 25 | Aer Lingus
        BRU 10:15
        23h 30m
        1 stop
        SOU 08:45
        Brussels - Southampton | Thu, Nov 27 | Aer Lingus
        £162 £346
        53% OFF
        53% OFF
        £346 £162
      • SOU 14:15
        7h 15m
        1 stop
        BRU 22:30
        Southampton - Brussels | Thu, Dec 25 | easyJet
        BRU 06:20
        8h 15m
        1 stop
        SOU 13:35
        Brussels - Southampton | Thu, Jan 1 | Swiss Airlines
        £193 £346
        44% OFF
        44% OFF
        £346 £193
      • SOU 09:30
        7h 45m
        1 stop
        BRU 18:15
        Southampton - Brussels | Mon, Nov 24 | Aer Lingus
        BRU 10:15
        23h 30m
        1 stop
        SOU 08:45
        Brussels - Southampton | Sat, Nov 29 | Aer Lingus
        £204 £346
        41% OFF
        41% OFF
        £346 £204
      • SOU 14:45
        5h 10m
        1 stop
        CRL 20:55
        Southampton - Brussels | Thu, Dec 4 | Loganair
        CRL 07:50
        11h
        1 stop
        SOU 17:50
        Brussels - Southampton | Sun, Dec 7 | Ryanair
        £242
        30% OFF
        £346 £242
      • SOU 09:25
        11h 55m
        1 stop
        BRU 22:20
        Southampton - Brussels | Sat, Dec 6 | KLM
        BRU 10:45
        7h 40m
        1 stop
        SOU 17:25
        Brussels - Southampton | Mon, Dec 8 | KLM
        £248
        28% OFF
        £346 £248
      • SOU 09:25
        3h 50m
        1 stop
        BRU 14:15
        Southampton - Brussels | Sat, Dec 13 | KLM
        BRU 06:15
        3h 35m
        1 stop
        SOU 08:50
        Brussels - Southampton | Sun, Dec 14 | KLM
        £248
        28% OFF
        £346 £248
      • SOU 18:05
        12h 30m
        1 stop
        BRU 07:35
        Southampton - Brussels | Thu, Dec 11 | KLM
        BRU 06:15
        3h 35m
        1 stop
        SOU 08:50
        Brussels - Southampton | Sun, Dec 14 | KLM
        £248
        28% OFF
        £346 £248
      • SOU 08:50
        4h 25m
        1 stop
        BRU 14:15
        Southampton - Brussels | Thu, Nov 20 | KLM
        BRU 14:45
        3h 15m
        1 stop
        SOU 17:00
        Brussels - Southampton | Wed, Nov 26 | KLM
        £249
        28% OFF
        £346 £249
      • SOU 17:30
        13h 5m
        1 stop
        BRU 07:35
        Southampton - Brussels | Fri, Nov 28 | KLM
        BRU 06:15
        3h 35m
        1 stop
        SOU 08:50
        Brussels - Southampton | Sun, Nov 30 | KLM
        £249
        28% OFF
        £346 £249
      • SOU 17:30
        13h 5m
        1 stop
        BRU 07:35
        Southampton - Brussels | Sat, Nov 22 | KLM
        BRU 10:45
        7h 15m
        1 stop
        SOU 17:00
        Brussels - Southampton | Sat, Nov 29 | KLM
        £249
        28% OFF
        £346 £249
      • SOU 13:00
        17h 25m
        1 stop
        BRU Invalid Date
        Southampton - Brussels | Mon, Nov 17 | Normal Airline
        BRU 15:00
        6h
        Direct
        SOU 16:00
        Brussels - Southampton | Wed, Nov 19 | Normal Airline
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Flight Information from Southampton to Brussels

The distance between Southampton and Brussels is about 409.24km. The most popular month to Brussels is January. The off-season for travel is December.

Cheapest one-way flight price£50
Cheapest return ticket price£162
Off-season travel monthDecember
Peak season for travelJanuary
Flight distance409.24km

Find the best time to fly from Southampton to Brussels

The cheapest time for Southampton to Brussels flights: Jan 4 to Jan 11 — one way flight prices from £49.

Cheapest flights
From price
Search
  • 916
  • 1623
  • 2330

  • Dec

    307
  • 714
  • 1421
  • 2128

  • Jan

    284
  • 411
  • 1118
  • 1825

  • Feb

    251
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

  • When is the best time to book flights from Southampton to Brussels?

    By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Southampton to Brussels is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • The cheapest months to fly from Southampton to Brussels is December, when demand for travel is lower.
  • After crunching the numbers on our November flight calendar, it's currently cheapest to fly from Southampton to Brussels on November 25, 2025 with Aer Lingus, with prices starting at £161.
  • The time difference between Brussels and Southampton is 1h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

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