Hotels in Santee

Hotels in Santee

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We found 13 hotels for you in Santee

Trip.com offers top-picked hotels in Santee, including reviews, price estimates, and facility details to help you choose the best option for you.
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Best Western Plus Santee Inn Hotels in Santee
Best Western Plus Santee Inn Hotels in SanteeBest Western Plus Santee Inn Hotels in SanteeBest Western Plus Santee Inn Hotels in SanteeBest Western Plus Santee Inn Hotels in SanteeBest Western Plus Santee Inn Hotels in SanteeBest Western Plus Santee Inn Hotels in Santee
47
Hotels in Santee
Golf Course
Outdoor swimming pool
Hiking
+6
"You double booked me at this hotel in error so I got charged twice but only one booking shows up in my account. I need to know how to get my money back for the false booking."
Very Good
101 reviews
8.5/10
1 night
From MYR 477
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Quality Inn & Suites Hotels in Santee
Quality Inn & Suites Hotels in SanteeQuality Inn & Suites Hotels in SanteeQuality Inn & Suites Hotels in SanteeQuality Inn & Suites Hotels in SanteeQuality Inn & Suites Hotels in SanteeQuality Inn & Suites Hotels in Santee
80
Hotels in Santee
Private parking
Wi-Fi in Public Areas
Golf Course
+6
Located in Santee, Quality Inn & Suites Santee I-95 is within a 15-minute walk of Santee Cooper Country Club and Santee State Park. This hotel is 24.9 mi (40.1 km) from Congaree National Park and 1.1 mi (1.7 km) from Santee National Golf Club. Take advantage of recreation opportunities such as a seasonal outdoor pool, or other amenities including complimentary wireless internet access and a fireplace in the lobby. Additional features at this hotel include a banquet hall and a vending machine. Grab a bite to eat at one of the hotel's many dining establishments, which include 7 restaurants and a coffee shop/cafe. Quench your thirst with your favorite drink at the bar/lounge. A complimentary full breakfast is served daily from 6:30 AM to 9:30 AM. Featured amenities include a business center, a 24-hour front desk, and multilingual staff. Free self parking is available onsite. Make yourself at home in one of the 106 air-conditioned rooms featuring LED televisions. Complimentary wireless internet access keeps you connected, and satellite programming is available for your entertainment. Bathrooms have bathtubs and hair dryers. Conveniences include desks and coffee/tea makers, as well as phones with free local calls.
98 reviews
6.0/10
1 night
From MYR 253
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Hampton Inn Santee Hotels in Santee
Hampton Inn Santee Hotels in SanteeHampton Inn Santee Hotels in SanteeHampton Inn Santee Hotels in SanteeHampton Inn Santee Hotels in SanteeHampton Inn Santee Hotels in SanteeHampton Inn Santee Hotels in Santee
99+
Hotels in Santee
Public parking
Fitness Room
Wi-Fi in Public Areas
+6
"The breakfast was good and the food was good. The rooms are large and the service is warm. be quiet. There are many restaurants around to eat, which is very convenient. Huanpeng's brand is not bad, the price is moderate, suitable for rest in the middle of the journey."
Amazing
98 reviews
9.6/10
1 night
From MYR 560
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Fairfield Inn & Suites Santee Hotels in Santee
Fairfield Inn & Suites Santee Hotels in SanteeFairfield Inn & Suites Santee Hotels in SanteeFairfield Inn & Suites Santee Hotels in SanteeFairfield Inn & Suites Santee Hotels in SanteeFairfield Inn & Suites Santee Hotels in SanteeFairfield Inn & Suites Santee Hotels in Santee
49
Hotels in Santee
Golf Course
Outdoor swimming pool
Hiking
+7
"I was extremely pleased with my overnight stay. As a Marriott Owner/Member, I try to find the perfect place to stay with my two small dogs. Dog owners are at a terrible disadvantage when finding a clean, safe hotel to stay. The Fairfield provided everything. The wonderful people at the front desk were so welcoming, the breakfast was delicious with many choices, and the carpets were spotless; you would never know animals were there. The outside grounds were clean and free from any animal deposits or human trash and beautiful flowers and trimmed landscaping was so pretty. In addition, guests were given welcome gift bags with bottled water and cookies. I will certainly be back!"
Amazing
108 reviews
9.7/10
1 night
From MYR 589
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Travelodge by Wyndham Santee Hotels in Santee
Travelodge by Wyndham Santee Hotels in SanteeTravelodge by Wyndham Santee Hotels in SanteeTravelodge by Wyndham Santee Hotels in SanteeTravelodge by Wyndham Santee Hotels in SanteeTravelodge by Wyndham Santee Hotels in SanteeTravelodge by Wyndham Santee Hotels in Santee
30
Hotels in Santee
Private parking
Wi-Fi in Public Areas
Golf Course
+2
"Ummmm wrong room given at start Breakfast was pieces of pastry cut up...o.o Coffee was beyond burnt Least it had a room to be safe from the elements"
99 reviews
7.2/10
1 night
From MYR 253
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Holiday Inn SANTEE by IHG Hotels in Santee
Holiday Inn SANTEE by IHG Hotels in SanteeHoliday Inn SANTEE by IHG Hotels in SanteeHoliday Inn SANTEE by IHG Hotels in SanteeHoliday Inn SANTEE by IHG Hotels in SanteeHoliday Inn SANTEE by IHG Hotels in SanteeHoliday Inn SANTEE by IHG Hotels in Santee
94
Hotels in Santee
Golf Course
Fitness Room
Public parking
+5
Just off I‑95 in Santee, South Carolina, the Holiday Inn Santee offers a relaxing stay near the shores of Lake Marion, one of the largest lakes in the state. Surrounded by peaceful Lowcountry scenery, our location provides easy access while still feeling removed from the rush of everyday travel. Lake Marion is a major draw for anglers, famous for striped bass, crappie, bream, and some of the biggest catfish in the Southeast. Guests are also close to Santee State Park for boating and hiking, Edisto Memorial Gardens for seasonal blooms and butterflies, and several well‑known golf courses. Columbia and historic Charleston are both within driving distance for sightseeing, dining, and cultural attractions. After a day on the lake or at meetings, enjoy amenities designed for comfort and convenience, including free Wi‑Fi, a 24‑hour Business Center, an indoor heated pool, and an on‑site restaurant serving comforting favorites. Warm Southern hospitality and a convenient location make every stay easy, productive, and enjoyable.
Very Good
99 reviews
8.2/10
1 night
From MYR 415
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Baymont by Wyndham Santee Hotels in Santee
Baymont by Wyndham Santee Hotels in SanteeBaymont by Wyndham Santee Hotels in SanteeBaymont by Wyndham Santee Hotels in SanteeBaymont by Wyndham Santee Hotels in SanteeBaymont by Wyndham Santee Hotels in SanteeBaymont by Wyndham Santee Hotels in Santee
53
Hotels in Santee
Public parking
Wake-Up Call
Wi-Fi in Public Areas
+3
"We are pleased our stay at Baymont Windham in Santee,SC. Clean room, good service, ideal location next to 95,."
Good
102 reviews
7.9/10
1 night
From MYR 300
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Tru by Hilton Santee Hotels in Santee
Tru by Hilton Santee Hotels in SanteeTru by Hilton Santee Hotels in SanteeTru by Hilton Santee Hotels in SanteeTru by Hilton Santee Hotels in SanteeTru by Hilton Santee Hotels in SanteeTru by Hilton Santee Hotels in Santee
51
Hotels in Santee
Indoor swimming pool
Fitness Room
Parking
+3
"Every time I drive back to New York from Florida, I will live here. It is convenient and clean. It also accepts pets. There is no microwave in the room. But there is a front desk downstairs. It is still very recommended."
Very Good
101 reviews
8.9/10
1 night
From MYR 439
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Ramada by Wyndham Santee I-95 Hotels in Santee
Ramada by Wyndham Santee I-95 Hotels in SanteeRamada by Wyndham Santee I-95 Hotels in SanteeRamada by Wyndham Santee I-95 Hotels in SanteeRamada by Wyndham Santee I-95 Hotels in SanteeRamada by Wyndham Santee I-95 Hotels in SanteeRamada by Wyndham Santee I-95 Hotels in Santee
32
Hotels in Santee
Public parking
Fitness Room
Wi-Fi in Public Areas
+10
Experience the charm and warmth of Southern hospitality at Ramada by Wyndham Santee I-95. Conveniently located just off I-95 and US-1559 miles from Charleston International Airport -CHS our hotel welcomes you with free WiFi and parking as well as a bar room service and outdoor pool. Our non-smoking hotel is minutes from South Carolina State University golf courses for a weekend getaway fishing on Lake Marion or the nature trails in Santee State Park.
53 reviews
6.6/10
1 night
From MYR 306
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Super 8 by Wyndham Santee Hotels in Santee
Super 8 by Wyndham Santee Hotels in SanteeSuper 8 by Wyndham Santee Hotels in SanteeSuper 8 by Wyndham Santee Hotels in SanteeSuper 8 by Wyndham Santee Hotels in SanteeSuper 8 by Wyndham Santee Hotels in SanteeSuper 8 by Wyndham Santee Hotels in Santee
38
Hotels in Santee
Private parking
Wi-Fi in Public Areas
Golf Course
+5
Make our Super 8 by Wyndham Santee/I-95 hotel your home base for golf and recreation in South Carolina. Located off I-95 halfway between New York City and Miami our hotel is a comfortable stopping point on your East Coast road trip.
68 reviews
6.9/10
1 night
From MYR 302
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Trip.com's insights for hotels in Santee

Plan smarter with Trip.com’s data-backed insights on travel seasons so that you can book your Santee hotel at the right time!

What is the cheapest day of the week for hotels in Santee?

Hotel rates in Santee are typically lowest on Thursday, with average nightly rates around MYR 479. Sunday tends to be the most expensive, averaging MYR 598 per night.
(Based on Trip.com data from July 2, 2025 to July 2, 2026.)
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Explore accommodation types in Santee

Immerse yourself in the vibrant atmosphere of Santee with our handpicked accommodation options

Top hotel picks in Santee

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Check out these top-booked hotels from the past 30 days!
Comfort Inn & Suites Santee I-95 Hotels in Santee
8.0/10
100 reviews

Comfort Inn & Suites Santee I-95

Hotel near Santee
Popular choice among guests booking hotels in Santee
Located in Santee, Comfort Inn & Suites Santee is in the entertainment district, within a 5-minute drive of Santee Cooper Country Club and Santee National Golf Club. This hotel is 24.5 mi (39.5 km) from Congaree National Park and 1.2 mi (1.9 km) from Santee Town Hall. Take advantage of recreation opportunities including a fitness center and a seasonal outdoor pool. Additional features at this hotel include complimentary wireless internet access, a fireplace in the lobby, and a vending machine. A complimentary buffet breakfast is included. Featured amenities include a business center, complimentary newspapers in the lobby, and a 24-hour front desk. Free self parking is available onsite. Make yourself at home in one of the 61 guestrooms featuring microwaves and plasma televisions. Your pillowtop bed comes with Frette Italian sheets. Complimentary wireless internet access keeps you connected, and satellite programming is available for your entertainment. Bathrooms have shower/tub combinations and hair dryers.
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Red Roof Inn Santee Hotels in Santee
6.5/10
84 reviews

Red Roof Inn Santee

Hotel near Santee
Popular choice among guests booking hotels in Santee
Red Roof Inn Santee offers a budget-friendly stay in the heart of "America's Value Golf Destination." Whether you're here for championship golf, lake recreation, or exploring the area, Red Roof Inn Santee provides dependable comfort and value in beautiful Santee, South Carolina. Red Roof Inn Santee is a welcoming and affordable choice for golf enthusiasts and families seeking relaxation near Lake Marion. With friendly service and thoughtful amenities, we make every stay simple and enjoyable. Guests can expect a pleasant stay with essentials, including free Wi-Fi, a free expanded cable package featuring HBO, a complimentary continental breakfast, and coffee in the lobby. Each room also features a microwave and mini-refrigerator for added convenience. We are proud to be a pet-friendly hotel, so your four-legged companion is always welcome. Our Santee, SC hotel is located near popular attractions such as Lake Marion Golf Course, Santee Cooper Country Club, Lake Marion, Santee State Park, the Santee National Wildlife Refuge, and the Santee Conference Center, all within easy reach.
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Econo Lodge Hotels in Santee
6.3/10
18 reviews

Econo Lodge

Hotel near Santee
Popular choice among guests booking hotels in Santee
A stay at Econo Lodge Santee places you in the heart of Santee, a short 4-minute walk from Santee Cooper Country Club and within 3 minutes by car from Santee National Golf Club. This hotel is 25.6 mi (41.1 km) from Congaree National Park and 1.4 mi (2.2 km) from Santee State Park. Take in the views from a garden and make use of amenities such as complimentary wireless internet access and barbecue grills. Featured amenities include a 24-hour front desk and luggage storage. Free self parking is available onsite. Make yourself at home in one of the 37 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have bathtubs and hair dryers. Conveniences include desks and microwaves, as well as phones with free local calls.
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FAQs About Hotels in Santee

What are some of the best hotels in Santee?

Which hotels in Santee are pet friendly?

Tru by Hilton Santee (from MYR 463) allows pets. Take your pets with you during your stay!

Which hotels in Santee have swimming pools?

Fairfield Inn & Suites Santee (from MYR 544), Hampton Inn Santee (from MYR 515) and Quality Inn & Suites (from MYR 180) are hotels with swimming pools. Stay at any of these hotels to enjoy a swimming pool!

What hotels in Santee offer an especially good breakfast ?

Fairfield Inn & Suites Santee (from MYR 544),Holiday Inn SANTEE by IHG (from MYR 456) and Tru by Hilton Santee (from MYR 463) provide high-quality breakfast. Start your day with a delicious breakfast!

How to get good deals on hotels in Santee?

To get the best hotel deals, try these Trip.com tips: 1. Log In Trip.com first and unlock member-only rates and Trip Coins (loyalty points). 2. Book Midweek: Sun–Thurs stays are much cheaper than weekends. 3. Set Price Alerts: Monitor price drops and rebook if needed. 4. Use “We Price Match” Policy: If you find a lower price elsewhere, Trip.com will refund the difference. 5. Avoid major holidays, conventions, and big events. 6. Check the Deals Page to see what promotions are available now on Trip.com.

Santee Hotels Information

Number of reviews
1,130
Total properties
13
Weekday Avg. Price
MYR 463
Weekend Avg. Price
MYR 561
Trending hotel
Fairfield Inn & Suites Santee