App
Customer Support
GBP
Find Bookings
Trip.com
>
Cheap Flights
>
Panama
>
Panama Province
>
Panama City
>
Flights from Madrid to Panama City
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Flights from Madrid to Panama City Starting at £276

For as little as £276, you can take your next adventure to Panama City without breaking the bank. Choose between one-way and return tickets from Madrid below.

  • One way
  • Round-trip
      • Cheapest nonstop
        MAD15:10
        10h 35m
        Nonstop
        PTY19:45
        Wed, Feb 12|Madrid - Panama City|Air Europa
        £276£405
        32% OFF
        32% OFF
        £405£276

        Choose Air Europa flights from Madrid to Panama City. The one-way direct flight with Air Europa departs from Madrid Barajas Airport on Wed, Feb 12, arriving at Tocumen International Airport. One-way Prices start from £276 including taxes and charges.

      • MAD15:10
        10h 35m
        Nonstop
        PTY19:45
        Fri, Feb 21|Madrid - Panama City|Air Europa
        £276£405
        32% OFF
        32% OFF
        £405£276

        Choose Air Europa flights from Madrid to Panama City. The one-way direct flight with Air Europa departs from Madrid Barajas Airport on Fri, Feb 21, arriving at Tocumen International Airport. One-way Prices start from £276 including taxes and charges.

      • MAD15:10
        10h 35m
        Nonstop
        PTY19:45
        Wed, Feb 19|Madrid - Panama City|Air Europa
        £276£405
        32% OFF
        32% OFF
        £405£276

        Choose Air Europa flights from Madrid to Panama City. The one-way direct flight with Air Europa departs from Madrid Barajas Airport on Wed, Feb 19, arriving at Tocumen International Airport. One-way Prices start from £276 including taxes and charges.

      • MAD15:10
        10h 35m
        Nonstop
        PTY19:45
        Mon, Feb 10|Madrid - Panama City|Air Europa
        £277
        £277

        Choose Air Europa flights from Madrid to Panama City. The one-way direct flight with Air Europa departs from Madrid Barajas Airport on Mon, Feb 10, arriving at Tocumen International Airport. One-way Prices start from £277 including taxes and charges.

      • MAD15:10
        10h 35m
        Nonstop
        PTY19:45
        Fri, Feb 7|Madrid - Panama City|Air Europa
        £278
        £278

        Choose Air Europa flights from Madrid to Panama City. The one-way direct flight with Air Europa departs from Madrid Barajas Airport on Fri, Feb 7, arriving at Tocumen International Airport. One-way Prices start from £278 including taxes and charges.

      • MAD15:10
        10h 35m
        Nonstop
        PTY19:45
        Sun, Feb 9|Madrid - Panama City|Air Europa
        £289
        £289

        Choose Air Europa flights from Madrid to Panama City. The one-way direct flight with Air Europa departs from Madrid Barajas Airport on Sun, Feb 9, arriving at Tocumen International Airport. One-way Prices start from £289 including taxes and charges.

      • MAD15:10
        10h 35m
        Nonstop
        PTY19:45
        Mon, Feb 24|Madrid - Panama City|Air Europa
        £290
        £290

        Choose Air Europa flights from Madrid to Panama City. The one-way direct flight with Air Europa departs from Madrid Barajas Airport on Mon, Feb 24, arriving at Tocumen International Airport. One-way Prices start from £290 including taxes and charges.

      • MAD15:10
        10h 35m
        Nonstop
        PTY19:45
        Tue, Feb 25|Madrid - Panama City|Air Europa
        £290
        £290

        Choose Air Europa flights from Madrid to Panama City. The one-way direct flight with Air Europa departs from Madrid Barajas Airport on Tue, Feb 25, arriving at Tocumen International Airport. One-way Prices start from £290 including taxes and charges.

      • MAD15:05
        10h 35m
        Nonstop
        PTY18:40
        Tue, Apr 1|Madrid - Panama City|Air Europa
        £304
        £304

        Choose Air Europa flights from Madrid to Panama City. The one-way direct flight with Air Europa departs from Madrid Barajas Airport on Tue, Apr 1, arriving at Tocumen International Airport. One-way Prices start from £304 including taxes and charges.

      • MAD15:05
        10h 35m
        Nonstop
        PTY18:40
        Wed, Apr 2|Madrid - Panama City|Air Europa
        £304
        £304

        Choose Air Europa flights from Madrid to Panama City. The one-way direct flight with Air Europa departs from Madrid Barajas Airport on Wed, Apr 2, arriving at Tocumen International Airport. One-way Prices start from £304 including taxes and charges.

      • MAD01:00 pm
        3h 5m
        Nonstop
        PTY02:00 pm
        Thu, Jan 30|Madrid - Panama City|Air Europa
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Madrid to Panama City flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AV047

    avianca

    01:30

    MAD

    10.5h

    05:00

    BOG

    SMTWTFS
    Search

  2. AV696

    avianca

    08:00

    BOG

    2.3h

    09:20

    SJO

    SMTWTFS

  3. AV643

    avianca

    10:15

    SJO

    1.3h

    12:35

    PTY

    SM-WTFS

  4. UX1065

    Air Europa

    07:40

    MAD

    2.1h

    09:45

    MXP

    SMTWTFS
    Search

  5. TK1876

    Turkish Airlines

    20:10

    MXP

    3.1h

    00:15

    IST

    SMTWTFS

  6. TK900

    Turkish Airlines

    09:40

    IST

    16.7h

    18:20

    PTY

    -M-----

  7. W46312

    Wizz Air Malta

    09:15

    MAD

    2.3h

    11:30

    MXP

    S--WTFS
    Search

  8. TK1878

    Turkish Airlines

    06:50

    MXP

    3.0h

    10:50

    IST

    SMTWTFS

  9. TK903

    Turkish Airlines

    14:10

    IST

    13.9h

    20:05

    PTY

    --T-T-S

  10. W46312

    Wizz Air Malta

    09:15

    MAD

    2.3h

    11:30

    MXP

    S--WTFS
    Search

  11. TK1876

    Turkish Airlines

    20:10

    MXP

    3.1h

    00:15

    IST

    SMTWTFS

  12. TK800

    Turkish Airlines

    09:40

    IST

    16.7h

    18:20

    PTY

    --T-T-S

  13. W46012

    Wizz Air Malta

    09:40

    MAD

    2.5h

    12:10

    FCO

    SMTWTFS
    Search

  14. TK1362

    Turkish Airlines

    07:00

    FCO

    2.8h

    10:45

    IST

    SMTWTFS

  15. TK903

    Turkish Airlines

    14:10

    IST

    13.9h

    20:05

    PTY

    --T-T-S

  16. IB673

    Iberia

    11:30

    MAD

    2.2h

    13:40

    MXP

    SMTWT--
    Search

  17. TK1876

    Turkish Airlines

    20:10

    MXP

    3.1h

    00:15

    IST

    SMTWTFS

  18. TK801

    Turkish Airlines

    09:10

    IST

    17.2h

    18:20

    PTY

    S--W-F-

  19. PU231

    Plus Ultra Lineas Aereas

    14:45

    MAD

    10.6h

    19:20

    BOG

    ---W---
    Search

  20. CM414

    Copa Airlines

    18:17

    BOG

    1.8h

    20:06

    PTY

    SMTWTFS

  21. PU221

    Plus Ultra Lineas Aereas

    14:55

    MAD

    10.5h

    18:25

    BOG

    S-T--F-
    Search

  22. AV060

    avianca

    14:40

    BOG

    1.8h

    16:30

    PTY

    SMTWTFS

  23. UX055

    Air Europa

    15:05

    MAD

    10.6h

    Nonstop

    18:40

    PTY

    SMT-TFS
    Search

  24. W46014

    Wizz Air Malta

    20:30

    MAD

    2.5h

    23:00

    FCO

    S-TWTFS
    Search

  25. TK1362

    Turkish Airlines

    07:00

    FCO

    2.8h

    10:45

    IST

    SMTWTFS

  26. TK903

    Turkish Airlines

    14:10

    IST

    13.9h

    20:05

    PTY

    --T-T-S
Find more flights and airlines

Find the best time to fly from Madrid to Panama City

Explore the best time to buy affordable tickets to Panama City with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Airlines Flying from Madrid to Panama City

Which airline provides the cheapest flights from Madrid to Panama City? Discover the option that best suits your travel needs before embarking on your journey.
Air Europa logoAir Europa

FAQ

  • When are flight tickets from Madrid (MAD) to Panama City (PTY) the cheapest?

    Airlines adjust prices for flights from Madrid to Panama City based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much are flights from Madrid (MAD) to Panama City (PTY) cost?

    According to Trip.com's data, the lowest price is around £804.

  • How long is the flight from Madrid (MAD) to Panama City (PTY)?

    It takes about 10 hours 47 minutes to fly from Madrid (MAD) to Panama City (PTY).

  • What is the transportation method from the main airport to downtown in Panama City?

    • The distance from Tocumen International Airport to downtown is about 16km, by taxi about 30 minutes.
    • The distance from Albrook "Marcos A. Gelabert" International Airport to downtown is about 5km, by taxi about 20 minutes.

  • What are the most popular airlines that fly from Madrid (MAD) to Panama City (PTY)?

    Airlines with flights from Madrid (MAD) to Panama City (PTY): Air Europa, Copa Airlines, Iberia, Qatar Airways, British Airways, Etihad Airways, El Al and China Eastern Airlines.

  • What's the most popular airline for direct flights from Madrid (MAD) to Panama City (PTY)?

    Iberia operates 2 direct flights from Madrid (MAD) to Panama City (PTY).

  • How many airports in Panama City (PTY)?

How to find a cheap flight from Madrid to Panama City

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information from Madrid to Panama City

Cheapest direct flight price£275
Cheapest return ticket price£426
Off-season travel monthJanuary
Peak season for travelOctober
Flight distance8,177.05km
Average flight time10 hours 47 minutes
Popular airlineavianca

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.