Cheap Flights from Medellin to San Francisco from £208️ (MDE-SFO)

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Latest Flight Deals from Medellin to San Francisco

Book one-way or return flights from Medellin to San Francisco from as little as £208. Choose from the popular airlines below and book your flight today!

One way
Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from Medellin to San Francisco? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from Medellin to San Francisco. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Airlines Flying from Medellin to San Francisco

View airlines operating flights from Medellin to San Francisco. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Spirit Airlines

From £174

JetSMART Airlines

From £188

Avianca

From £193

Copa Airlines

From £206

Jetblue Airways

From £208

LATAM Airlines

From £227

American Airlines

From £287

Delta Air Lines

From £292

Aeromexico

From £320

United Airlines

From £393

ANA airlines

Find more flights and airlines

Alternative Routes from Medellin to San Francisco

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Medellin to San Francisco.

Cheapest
MDE
01:26
23h 24m
2 transfer
SFO
22:50
Jose Marie Cordova Airport - San Francisco International Airport
Fri, May 3Spirit Airlines
£174
MDE
01:26
23h 24m
2 transfer
SFO
22:50
Jose Marie Cordova Airport - San Francisco International Airport
Fri, May 3Spirit Airlines
£174
Find More Flights

How do I find the cheapest flights?

When are flight tickets from Medellin (MDE) to San Francisco (SFO) the cheapest?
Airlines adjust prices for flights from Medellin to San Francisco based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much are flights from Medellin (MDE) to San Francisco (SFO) cost?
According to Trip.com's data, the lowest price is around £517.
What is the transportation method from the main airport to downtown in San Francisco?
- The distance from San Francisco International Airport to downtown is about 17km, by taxi about 30 minutes.
How many airports in San Francisco (SFO)?
There are 1 airport(s) in San Francisco (SFO): San Francisco International Airport.

How to find a cheap flight from Medellin to San Francisco

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Medellin to San Francisco. Book your flights at the right time and save more.

Book Early

Once prices are gone, they're gone. Lock in deals while you can!

Compare Flight Prices

Compare prices on travel agency and airline websites.

Look Out for Deals

Check airline and travel agency websites for latest flight deals

Check One-way Fares

Buying two cheap one-way flights can sometimes be a better deal than a round-trip.

Try Different Dates

Flying during the week, early in the morning, or late at night can help save money.

Use the Trip.com App

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