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Latest Flight Deals from Panama City to Mexico City

Book one-way or return flights from Panama City to Mexico City from as little as £123. Choose from the popular airlines below and book your flight today!

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from Panama City to Mexico City? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from Panama City to Mexico City. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Airlines Flying from Panama City to Mexico City

View airlines operating flights from Panama City to Mexico City. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Avianca
From £123
Copa Airlines
From £218
United Airlines
From £342
American Airlines
From £491
Delta Air Lines
From £535
ANA airlines

Find more flights and airlines

Alternative Routes from Panama City to Mexico City

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Panama City to Mexico City.

  • Cheapest
    Avianca
    PTY
    11:40
    12h 20m
    1 transfer
    MEX
    23:00
    Tocumen International Airport - Mexico City International Airport
    Sun, May 5Avianca
    £123
  • Avianca
    PTY
    17:40
    12h 50m
    1 transfer
    NLU
    05:30
    Tocumen International Airport - Felipe Ángeles International Airport
    Wed, May 1Avianca
    £224
  • United Airlines
    PTY
    10:00
    13h 25m
    2 transfer
    TLC
    22:25
    Tocumen International Airport - Toluca Airport
    Wed, May 22United Airlines
    £647
  • United Airlines
    PTY
    10:00
    13h 25m
    2 transfer
    TLC
    22:25
    Tocumen International Airport - Toluca Airport
    Wed, May 22United Airlines
    £647
    Find More Flights

How do I find the cheapest flights?

  • When are flight tickets from Panama City (PTY) to Mexico City (MEX) the cheapest?

    Airlines adjust prices for flights from Panama City to Mexico City based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much are flights from Panama City (PTY) to Mexico City (MEX) cost?

    According to Trip.com's data, the lowest price is around £467.
  • How long is the flight from Panama City (PTY) to Mexico City (MEX)?

    It takes about 3 hours 51 minutes to fly from Panama City (PTY) to Mexico City (MEX).
  • What is the transportation method from the main airport to downtown in Mexico City?

    • The distance from Mexico City International Airport to downtown is about 6km, by taxi about 20 minutes.
    • The distance from Felipe Ángeles International Airport to downtown is about 35km, by taxi about 50 minutes.
    • The distance from Toluca Airport to downtown is about 47km, by taxi about 1 hour.
  • What are the most popular airlines that fly from Panama City (PTY) to Mexico City (MEX)?

    Airlines with flights from Panama City (PTY) to Mexico City (MEX): Copa Airlines and Emirates.
  • What's the most popular airline for direct flights from Panama City (PTY) to Mexico City (MEX)?

    Copa Airlines operates 3 direct flights from Panama City (PTY) to Mexico City (MEX).
  • How many airports in Mexico City (MEX)?

How to find a cheap flight from Panama City to Mexico City

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Panama City to Mexico City. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com
Flight Information from Panama City to Mexico City

Cheapest direct flight price

£123

Cheapest return ticket price

£314

Cheapest month

January

Peak season for travel

October

Flight distance

2,403.84km

Average flight time

3 hours 51 minutes

Popular airline

Avianca