Flights from Santa Maria to Brussels Starting at £161

We've found these cheap flights for you. You can book one-way or return flight tickets.

Round-trip
One way

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

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Cheapest flights

From price

16 23
23 30
Apr

30 6
6 13
13 20
20 27
May

27 4
4 11
11 18
18 25
Jun

25 1
1 8

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

When are flight tickets from Santa Maria (SMA) to Brussels (BRU) the cheapest?

Airlines adjust prices for flights from Santa Maria to Brussels based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much are flights from Santa Maria (SMA) to Brussels (BRU) cost?

According to Trip.com's data, the lowest price is around £243.
What is the transportation method from the main airport to downtown in Brussels?
- The distance from Brussels National Airport to downtown is about 10km, by taxi about 30 minutes.
- The distance from Brussels South Charleroi Airport to downtown is about 43km, by taxi about 1 hour.
How many airports in Brussels (BRU)?

There are 2 airport(s) in Brussels (BRU): Brussels National Airport and Brussels South Charleroi Airport.

How to find a cheap flight from Santa Maria to Brussels

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Santa Maria to Brussels. Book your flights at the right time and save more.

Be flexible with your travel dates to get the cheapest flight from Santa Maria to Brussels.

Simply tap "Date" on the flight search bar to browse through the calendar and check out airfare from Santa Maria to Brussels over the next 6 months in 2025. If you're planning to fly within the next three months, it looks like the most affordable option is on Sun, Apr 13, with one-way flights priced at just £161.

Compare cheap flight deals from Santa Maria to Brussels across hundreds of airlines.

With our extensive search, you can compare prices from over 500 airlines to find the cheapest flight tickets from Santa Maria to Brussels. The cheapest airline for this route is Azores Airlines.

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Book early or wait until the last minute.

It's usually best to book early. Flight tickets are often cheapest when they're first released, typically about a year before the departure date. So, have a look online as soon as the flights you're interested in become available. If you miss the cheapest time, you might still find some good deals as the departure date gets closer.

Search for flights on the go.

For the best travel flight booking experience, download the Trip.com app. You can search for cheap flights from Santa Maria to Brussels and snag some exclusive deals just for you.

Flight Information from Santa Maria to Brussels

Cheapest one-way flight price	£161
Off-season travel month	June
Peak season for travel	April
Flight distance	2,805.4km
Popular airline	Azores Airlines