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Flights from Medellin to Santiago

Airlines Flying from Medellin to Santiago

Choose from 1 carriers that fly from Medellin to Santiago, including JetSMART Airlines, Enjoy the cheapest tickets on this route with JetSMART Airlines.
JetSMART Airlines logo JetSMART Airlines

Flight deals from Medellin to Santiago

Find the cheapest flights from Medellin to Santiago within the next three months. Book one-way flights from IDR 2,518,266 or return tickets from IDR 4,334,456.

Deals on upcoming return flights from Medellin to Santiago

Deals on upcoming one-way flights from Medellin to Santiago

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Flight Information from Medellin to Santiago

The distance between Medellin and Santiago is about 4,435.22km. The most popular month to Santiago is March. The off-season for travel is May.

Cheapest one-way flight priceIDR 2,518,266
Cheapest return ticket priceIDR 4,334,456
Off-season travel monthMay
Peak season for travelMarch
Flight distance4,435.22km
Popular airlineJetSMART

Find the best time to fly from Medellin to Santiago

The cheapest time for Medellin to Santiago flights: Sep 28 to Oct 5 — one way flight prices from IDR 2,518,265.

Cheapest flights
From price
Search
  • 714
  • 1421
  • 2128

  • Oct

    285
  • 512
  • 1219
  • 1926

  • Nov

    262
  • 29
  • 916
  • 1623
  • 2330
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

FAQ

  • What are the cheapest flights from Medellin to Santiago (MDE-SCL)?

    Based on Trip.com data, JetSMART Airlines offers one-way fares as low as IDR 2,518,266 on Cheapest nonstop routes (e.g. MDE to SCL on Fri, Oct 3), while JetSMART Airlines offers Cheapest nonstop round-trips from IDR 4,334,456 departing on Sun, Oct 5 and returning on Tue, Oct 7.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Medellin to Santiago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Medellin to Santiago, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Fri, Oct 3, with one-way flights priced at just IDR 2,518,266.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is JetSMART Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Santiago travel is around March.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Medellin to Santiago is May, when demand for travel is lower.
  • After crunching the numbers on our September flight calendar, it's currently cheapest to fly from Medellin to Santiago on September 28, 2025 with JetSMART, with prices starting at IDR 4,682,040.
  • The time difference between Santiago and Medellin is 1h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

How to find a cheap flight from Medellin to Santiago

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Medellin to Santiago. Book your flights at the right time and save more.
1
Be flexible with your travel dates to get the cheapest flight from Medellin to Santiago.
Simply tap "Date" on the flight search bar to browse through the calendar and check out airfare from Medellin to Santiago over the next 6 months in 2025. If you're planning to fly within the next three months, it looks like the most affordable option is on Fri, Oct 3, with one-way flights priced at just IDR 2518266.
2
Compare cheap flight deals from Medellin to Santiago across hundreds of airlines.
With our extensive search, you can compare prices from over 500 airlines to find the cheapest flight tickets from Medellin to Santiago. The cheapest airline for this route is JetSMART Airlines.
3
Set up a Price Alert
By setting up a Price Alert for your journey from Medellin to Santiago, you can easily keep an eye on ticket prices without having to check every day.
4
Don't miss out on cheap flight deals and promo codes from Medellin to Santiago.
You can always find the latest offers through Trip.com Deals and Promo Codes for cheap flights. By signing up for a free membership, you'll get access to even more deals for your flights.
5
Book early or wait until the last minute.
It's usually best to book early. Flight tickets are often cheapest when they're first released, typically about a year before the departure date. So, have a look online as soon as the flights you're interested in become available. If you miss the cheapest time, you might still find some good deals as the departure date gets closer.
6
Search for flights on the go.
For the best travel flight booking experience, download the Trip.com app. You can search for cheap flights from Medellin to Santiago and snag some exclusive deals just for you.

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