Looking for the perfect place to pamper yourself in Greenville? From sky-high suites overlooking the city's landmarks to tranquil resorts, Greenville offers an exceptional collection of luxury hotels that blend world-class comfort with signature local charm.

Whether you're here for a romantic getaway, honeymoon, or business retreat, these top-rated hotels promise indulgence at every moment.

Top-rated 5-star hotels in Greenville

If you love impeccable service and state-of-the-art amenities, these hotels deliver the full luxury experience. Expect infinity pools with panoramic views of Greenville, fine-dining restaurants helmed by renowned chefs, and wellness centers offering world-class spa treatments.

Luxury hotels with exceptional views

Whether it's the glittering skyline, the serenity of nature, or the cultural beauty of city landmarks, these luxury hotels are designed to impress. Enjoy sunset cocktails on private terraces, floor-to-ceiling windows in your suite, and romantic dinners set against stunning backdrops.

Luxury hotels near Greenville

If you're planning to explore beyond Greenville, there are plenty of luxurious getaways nearby. These hotels combine peaceful surroundings with easy access to the city, making them ideal for weekend retreats or extended vacations.

Each of these properties offers a unique escape within 1–3 hours of Greenville, making them perfect for travelers who want to combine urban excitement with tranquil luxury.

What makes Greenville's luxury hotels special

• Spectacular cityscapes: Wake up to panoramic views of Greenville.
• Gourmet dining: Many properties house Michelin-starred or award-winning restaurants.
• Exclusive wellness: From thermal spas to infinity pools, relaxation is redefined.
• Design & craftsmanship: Where modern elegance meets local artistry— a hallmark of Greenville's luxury scene.

Tips for booking luxury hotels in Greenville

1. Visit during shoulder seasons to enjoy ideal weather and fewer crowds.
2. Book early during festive seasons as top properties fill fast.
3. Compare prices and packages on Trip.com for exclusive member rates, loyalty points, and bundle discounts.
4. Consider weekday stays for better deals on premium suites.

Book your stay at Greenville's best luxury hotels

Ready to elevate your stay in Greenville? Explore Trip.Best's curated list of luxury hotels and experience premium comfort, world-class dining, and unbeatable service.

Book your perfect luxury escape on Trip.com today, where extraordinary stays begin.